Open Close
General Information
Symbol
Dmel\RhoGEF2HMS01118
Species
D. melanogaster
Name
FlyBase ID
FBal0257781
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Wounded embryos expressing RhoGEF2HMS01118 under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 show wound overexpansion, delayed actin accumulation around the wound edge and delayed repair, as compared to wounded control embryos.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The clonal co-expression of either l(2)glGD4047 and RhoGEF2HMS01118 or scribKK101128 and RhoGEF2HMS01118 under the control of Scer\GAL4Act5C.PI (together with Dicer-2, for efficient RNAi) in third instar larval wing discs leads to a significant proportion of apical delamination, which does not occur upon l(2)glGD4047 or scribKK101128 single expression clones.

The clonal co-expression of scribKK101128, RhoGEF2HMS01118 and Stat92EΔNΔC.UASp.Tag:HA under the control of Scer\GAL4Act5C.PI (together with Dicer-2, for efficient RNAi) in third instar larval wing discs leads to overgrowths in the wing pouch domain, which does not occur upon scribKK101128 single expression or scribKK101128, RhoGEF2HMS01118 double expression.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
RhoGEF2HMS01118
RhoGEF2RNAi(1)
Name Synonyms
Secondary FlyBase IDs
    References (6)