FlyBase Allele Report: Dmel\Delta[HMS01309]

General Information

Symbol

Dmel\Delta^HMS01309

Species

D. melanogaster

Name

FlyBase ID

FBal0257902

Feature type

allele

Associated gene

Dmel\Delta

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS01309}

Also Known As

UAS-Delta-RNAi, UAS.Dl shRNA

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS01309}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS01309

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates brain cancer

modeled by Vps35^E42

(Li et al., 2018)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell number | larval stage, with Scer\GAL4^wor.PA, Scer\GAL80^ase.PN

(Zhang et al., 2024)

Phenotype Manifest In

type II neuroblast | decreased number | larval stage, with Scer\GAL4^wor.PA, Scer\GAL80^ase.PN

(Zhang et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Delta^HMS01309/Scer\GAL4^pnt-14-94 is a suppressor of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Delta^HMS01309/Scer\GAL4^GMR9D11 is a suppressor of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407/Delta^HMS01309 is a suppressor of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Delta^HMS01309/Scer\GAL4^pnt-14-94 is a suppressor of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Delta^HMS01309/Scer\GAL4^GMR9D11 is a suppressor of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407/Delta^HMS01309 is a suppressor of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL80^ase.PN, Delta^HMS01309, Scer\GAL4^wor.PA is a suppressor of larval brain | larval stage phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, numb^HMS01459

(Zhang et al., 2024)

Scer\GAL80^ase.PN, Delta^HMS01309, Scer\GAL4^wor.PA is a suppressor of larval brain | larval stage phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brat^HMS01121

(Zhang et al., 2024)

Delta^HMS01309/Scer\GAL4^GMR9D11 is a suppressor of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407/Delta^HMS01309 is a suppressor of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Delta^HMS01309/Scer\GAL4^pnt-14-94 is a suppressor of larval neuroblast | increased number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Delta^HMS01309/Scer\GAL4^GMR9D11 is a suppressor of larval neuroblast | increased number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407/Delta^HMS01309 is a suppressor of larval neuroblast | increased number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Delta^HMS01309/Scer\GAL4^pnt-14-94 is a suppressor of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

34322

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01309}attP2

NIG-Fly

HMS01309

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01309}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Delta^HMS01309

Dl^HMS01309

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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