Allele Scer\GAL4^hs.PU

General Information
Symbol	Scer\GAL4^hs.PU	Species	S. cerevisiae
Name	heat shock construct of Unknown	FlyBase ID	FBal0258039
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02	Controlled Vocabulary Terms gravitaxis defective
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Chang et al., 2011)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\GAL4 is expressed under the control of a heat shock promoter. (Chang et al., 2011)
Carried in construct	P{hs-GAL4.U} (Kamimura et al., 2011, Hongay and Orr-Weaver, 2011, Mukai et al., 2011, Sarno et al., 2011, Lippai et al., 2008, Ishida et al., 2012, Kanuka et al., 2005, Wu et al., 2007, Marek and Kagan, 2012, Shao et al., 2011, Nakamoto et al., 2012, Chang et al., 2011, He et al., 2010, Francis et al., 2010, Bahri et al., 2010, Liu et al., 2011, Skora and Spradling, 2010, Anh et al., 2011, Sekine et al., 2011, Lee et al., 2011, Rhea et al., 2010, Clark et al., 2011, Yao and Carlson, 2010, Peng et al., 2009, Wong et al., 2012, Bolukbasi et al., 2012, Fichelson et al., 2012, Jones et al., 2012, Davis et al., 2008, Choi et al., 2007, Lee and Chung, 2007, Pereira et al., 2006, Nie et al., 2012, Taniguchi et al., 2007, Sese et al., 2006, Boyles et al., 2010, Peru Y Colón de Portugal et al., 2012, Sekine et al., 2012, Popkova et al., 2012, Lee et al., 2008, Melom and Littleton, 2013, Jin et al., 2008, Garcia-Lopez et al., 2008, Tanenhaus et al., 2012, Schaefer et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class
	body color defective \| heat sensitive, with Pk92B^{ΔN.Scer\UAS.T:Zzzz\FLAG} (Sekine et al., 2011) gravitaxis defective \| heat sensitive, with nej^{dsRNA.Scer\UAS.cKa} (Boyles et al., 2010) heat stress response defective, with Pgam5^NIG.14816R (Ishida et al., 2012) increased cell death \| third instar larval stage, with Zzzz\aopP^{Scer\UAS.T:Hsap\MYC} (Jones et al., 2012) lethal \| heat sensitive, with amon^{dsRNA.Scer\UAS.cBa} (Rhea et al., 2010) lethal \| heat sensitive, with Zzzz\aopP^{Scer\UAS.T:Hsap\MYC} (Jones et al., 2012) memory defective \| heat sensitive, with Nmdar1^{dsRNA.Scer\UAS.cWa} (Wu et al., 2007) neurophysiology defective \| heat sensitive, with Gαq^{Q203L.Scer\UAS} (Yao and Carlson, 2010) smell perception defective \| heat sensitive, with Gαq^{Q203L.Scer\UAS} (Yao and Carlson, 2010)
Phenotype Manifest In
	adult olfactory receptor neuron Gr21a/63a \| heat sensitive, with Gαq^{Q203L.Scer\UAS} (Yao and Carlson, 2010) adult thorax \| heat sensitive, with Pk92B^{ΔN.Scer\UAS.T:Zzzz\FLAG} (Sekine et al., 2011) anterior embryonic/larval midgut \| heat sensitive, with puc^Scer\UAS.cMa (Taniguchi et al., 2007) egg chamber, with Ime4^GD9882 (Hongay and Orr-Weaver, 2011) egg chamber \| conditional, with Pax^{Scer\UAS.T:Avic\GFP} (He et al., 2010) egg chamber \| conditional, with rhea^VDRC.cUa (He et al., 2010) egg chamber \| conditional, with rok^VDRC.cUa (He et al., 2010) fat body, with Zzzz\aopP^{Scer\UAS.T:Hsap\MYC} (Jones et al., 2012) wing \| heat sensitive, with Pk92B^{ΔN.Scer\UAS.T:Zzzz\FLAG} (Sekine et al., 2011)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference osa^Scer\UAS.cCa/Scer\GAL4^hs.PU is a suppressor of visible \| dominant phenotype of gcm^Pyx (Popkova et al., 2012)
Phenotype Manifest In
Suppressor of
Statement Reference Lpin^EP2431/Scer\GAL4^hs.PU is a suppressor of wing vein phenotype of Dd^G0269 (Liu et al., 2011) osa^Scer\UAS.cCa/Scer\GAL4^hs.PU is a suppressor of chaeta \| supernumerary phenotype of gcm^Pyx (Popkova et al., 2012) Pak3^{Scer\UAS.T:Avic\GFP}/Scer\GAL4^hs.PU is a suppressor \| partially of embryonic/larval cuticle phenotype of Pak3^76A, Pak¹⁴ (Bahri et al., 2010) Scer\GAL4^hs.PU, Scer\GAL4^GMR.PF, Hsap\EYS^Scer\UAS.cNa is a suppressor \| partially of eye phenotype of eys¹ (Nie et al., 2012) Scer\GAL4^hs.PU, Scer\GAL4^GMR.PF, Hsap\EYS^Scer\UAS.cNa is a suppressor \| partially of rhabdomere phenotype of eys¹ (Nie et al., 2012) shg^{Scer\UAS.T:Avic\GFP-rs}/Scer\GAL4^hs.PU is a suppressor \| partially of egg chamber phenotype of Inx2^FA42 (Mukai et al., 2011)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Arfip^{Scer\UAS.T:Ivir\HA1}/Scer\GAL4^hs.PU rescues Arfip⁷¹/Arfip¹² (Peru Y Colón de Portugal et al., 2012) Dd^Scer\UAS.cLa/Scer\GAL4^hs.PU rescues Dd^G0269 (Liu et al., 2011) Dd^{Scer\UAS.T:Ivir\HA1}/Scer\GAL4^hs.PU rescues Dd^G0269 (Liu et al., 2011) dysb^Scer\UAS.cSa/Scer\GAL4^hs.PU rescues dysb^e01028 (Shao et al., 2011) Lmpt^GE27535/Scer\GAL4^hs.PU rescues Lmpt^GE27535 (Jin et al., 2008) Myd88^{Scer\UAS.T:Hsap\PLCD1}/Scer\GAL4^hs.PU rescues Myd88^c03881 (Marek and Kagan, 2012) Pcl^GE15295/Scer\GAL4^hs.PU rescues Pcl^GE15295 (Jin et al., 2008) poly^Scer\UAS.cBa/Scer\GAL4^hs.PU rescues poly⁰⁵¹³⁷ (Bolukbasi et al., 2012) Scer\GAL4^hs.PU, inv^GE10665 rescues inv^GE10665 (Jin et al., 2008) Scer\GAL4^hs.PU, jumu^GE27806 rescues jumu^GE27806 (Jin et al., 2008) Scer\GAL4^hs.PU, pic^GE28589 rescues pic^GE28589 (Jin et al., 2008) Scer\GAL4^hs.PU, Trx-2^GE14911 rescues Trx-2^GE14911 (Jin et al., 2008) Scer\GAL4^hs.PU/CG12004^GE25730 rescues CG12004^GE25730 (Jin et al., 2008) Scer\GAL4^hs.PU/CG12744^GE13306 rescues CG12744^GE13306 (Jin et al., 2008) Scer\GAL4^hs.PU/Myd88^Scer\UAS.cMa rescues Myd88^c03881 (Marek and Kagan, 2012) Scer\GAL4^hs.PU/Uvrag^{Scer\UAS.T:Zzzz\FLAG} rescues Uvrag^KG04163/Uvrag^B21 (Lee et al., 2011)
Partially rescues	Inx2^Scer\UAS.cBa/Scer\GAL4^hs.PU partially rescues Inx2^FA42 (Mukai et al., 2011) puc^Scer\UAS.cMa/Scer\GAL4^hs.PU partially rescues puc^GS16811 (Taniguchi et al., 2007) Scer\GAL4^hs.PU/Myd88^{Cyto.Scer\UAS} partially rescues Myd88^c03881 (Marek and Kagan, 2012) Scer\GAL4^hs.PU/SNF4Aγ^Scer\UAS.RG partially rescues SNF4Aγ^S005042 (Lippai et al., 2008)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Scer\GAL4^hs.PU
Name Synonym	heat shock construct of Unknown
Secondary FlyBase IDs

References ( 45 )

Generate a list of	All references relating to this allele ( 45 )

List References by type	Research paper ( 44 ) Supplementary material ( 1 )
Recent research papers ( 24 )
	Melom and Littleton, 2013, J. Neurosci. 33(3): 1169--1178 Mutation of a NCKX Eliminates Glial Microdomain Calcium Oscillations and Enhances Seizure Susceptibility. [FBrf0220564] Bolukbasi et al., 2012, Open Biol. 2(1): 110031 Drosophila poly suggests a novel role for the Elongator complex in insulin receptor-target of rapamycin signalling. [FBrf0218466] Fichelson et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(20): 7893--7898 Orthodenticle and Kruppel homolog 1 regulate Drosophila photoreceptor maturation. [FBrf0218313] Ishida et al., 2012, PLoS ONE 7(2): e30265 Prevention of Apoptosis by Mitochondrial Phosphatase PGAM5 in the Mushroom Body Is Crucial for Heat Shock Resistance in Drosophila melanogaster. [FBrf0217492] Jones et al., 2012, Cell. Microbiol. 14(2): 274--285 Aeromonas salmonicida-secreted protein AopP is a potent inducer of apoptosis in a mammalian and a Drosophila model. [FBrf0217270] Marek and Kagan, 2012, Immunity 36(4): 612--622 Phosphoinositide Binding by the Toll Adaptor dMyD88 Controls Antibacterial Responses in Drosophila. [FBrf0218122] Nakamoto et al., 2012, Immunity 36(4): 658--667 Virus recognition by toll-7 activates antiviral autophagy in Drosophila. [FBrf0218107] Nie et al., 2012, Dev. Biol. 371(2): 312--320 Cross species analysis of Prominin reveals a conserved cellular role in invertebrate and vertebrate photoreceptor cells. [FBrf0219508] Peru Y Colón de Portugal et al., 2012, J. Neurosci. 32(49): 17706--17713 Adult Neuronal Arf6 Controls Ethanol-Induced Behavior with Arfaptin Downstream of Rac1 and RhoGAP18B. [FBrf0220158] Popkova et al., 2012, PLoS Genet. 8(12): e1003159 Polycomb controls gliogenesis by regulating the transient expression of the gcm/glide fate determinant. [FBrf0220515] Sekine et al., 2012, Mol. Cell 48(5): 692--704 The Kelch Repeat Protein KLHDC10 Regulates Oxidative Stress-Induced ASK1 Activation by Suppressing PP5. [FBrf0220253] Tanenhaus et al., 2012, PLoS ONE 7(10): e45130 In Vivo Circadian Oscillation of dCREB2 and NF-κB Activity in the Drosophila Nervous System. [FBrf0219734] Wong et al., 2012, Cell 148(5): 1029--1038 Neuropeptide delivery to synapses by long-range vesicle circulation and sporadic capture. [FBrf0217647] Anh et al., 2011, J. Biol. Chem. 286(38): 33244--33251 Essential role of duox in stabilization of Drosophila wing. [FBrf0215569] Chang et al., 2011, PLoS Genet. 7(2): e1001288 Pathogenic VCP/TER94 Alleles Are Dominant Actives and Contribute to Neurodegeneration by Altering Cellular ATP Level in a Drosophila IBMPFD Model. [FBrf0213008] Clark et al., 2011, Curr. Biol. 21(19): 1672--1677 Multiple TGF-β Superfamily Signals Modulate the Adult Drosophila Immune Response. [FBrf0216429] Hongay and Orr-Weaver, 2011, Proc. Natl. Acad. Sci. U.S.A. 108(36): 14855--14860 Drosophila Inducer of MEiosis 4 (IME4) is required for Notch signaling during oogenesis. [FBrf0215277] Kamimura et al., 2011, Glycobiology 21(5): 607--618 In vivo manipulation of heparan sulfate structure and its effect on Drosophila development. [FBrf0213406] Lee et al., 2011, Dev. Biol. 356(2): 588--597 UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila. [FBrf0214470] Liu et al., 2011, Dev. Growth Differ. 53(6): 822--841 Negative modulation of bone morphogenetic protein signaling by Dullard during wing vein formation in Drosophila. [FBrf0214664] Mukai et al., 2011, Mech. Dev. 128(7-10): 510--523 Innexin2 gap junctions in somatic support cells are required for cyst formation and for egg chamber formation in Drosophila. [FBrf0216750] Sarno et al., 2011, Int. J. Dev. Biol. 55(10-11-12): 975--979 Effect of the transformer-2 gene of Anastrepha on the somatic sexual development of Drosophila. [FBrf0217213] Sekine et al., 2011, J. Cell Sci. 124(17): 3006--3016 p38 MAPKs regulate the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors. [FBrf0215011] Shao et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(46): 18831--18836 Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila. [FBrf0216775] Show all research papers ...

Allele Scer\GAL4hs.PU

Allele Scer\GAL4^hs.PU