FB2025_01 , released February 20, 2025
Allele: Dmel\RhebUAS.cUa
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General Information
Symbol
Dmel\RhebUAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0258444
Feature type
allele
Associated gene
Dmel\Rheb
Associated Insertion(s)
Carried in Construct
P{UAS-Rheb.U}
Also Known As
UAS-Rheb
Key Links
Transgenic product class
wild_type
(Nisoli et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Nisoli et al., 2010)
Mutagen
in vitro construct
(Nisoli et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Rheb.U}
Cytology
Description

UAS regulatory sequences drive expression of Rheb.

(Nisoli et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Rheb
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adults expressing RhebUAS.cUa under the control of Scer\GAL4ppl.PP are resistant to starvation.

      (Pathak and Varghese, 2021)

      Expressing RhebUAS.cUa under the control of Scer\GAL4ptc.PU leads to a significant increase in size of the wing blade domain between L3 and L4 veins.

      (Kim and Choi, 2019)

      Overexpression of RhebScer\UAS.cUa driven by Scer\GAL4C7 induces mild but significant decreases in male and female body size (body weight measured at pharate adult stage), does not significantly affect larval growth rates, and slightly but significantly reduces the duration of the third instar larval stage.

      (Koyama and Mirth, 2016)

      Scer\GAL4Cg.PA RhebScer\UAS.cUa animals have wings of normal size that contain abnormally large cells.

      (Parisi et al., 2013)

      Expression of RhebScer\UAS.cUa under the control of Scer\GAL4en.PU results in an increase in size of the posterior compartment of the wing.

      (Pallares-Cartes et al., 2012)

      Central nervous system neuroblasts of larvae expressing RhebScer\UAS.cUa under the control of Scer\GAL4Cg.PA and raised on a diet lacking amino acids for 24 hours show no significant difference in EdU incorporation compared to controls.

      Central nervous system neuroblasts of fed larvae expressing RhebScer\UAS.cUa under the control of Scer\GAL4nab show an increase in EdU incorporation compared to controls.

      Central nervous system neuroblasts of larvae expressing RhebScer\UAS.cUa under the control of Scer\GAL4nab and raised on a diet lacking amino acids for 24 hours show an increase in EdU incorporation compared to controls.

      (Sousa-Nunes et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of RhebScer\UAS.cUa under the control of Scer\GAL4Tab2-201Y partially rescues the gamma lobe regrowth defects of Eip75BΔ51/Eip75BΔ51 mushroom body neuron clones.

      (Rabinovich et al., 2016)

      Co-expression of RhebScer\UAS.cUa partially rescues the reduction in size of the posterior compartment of the wing which is caused by expression of PRAS40Scer\UAS.cCa under the control of Scer\GAL4en.PU.

      (Pallares-Cartes et al., 2012)

      Expression of RhebScer\UAS.cUa under the control of Scer\GAL4Cg.PA suppresses the increase in Lysotracker-positive vesicle volume seen in trpml1 mutant fat body cells.

      (Wong et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      RhebScer\UAS.cUa
      RhebUAS.cUa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Unknown
      Secondary FlyBase IDs
        References (16)