FB2025_01 , released February 20, 2025
Allele: Dmel\dsxf00683-d07058
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General Information
Symbol
Dmel\dsxf00683-d07058
Species
D. melanogaster
Name
FlyBase ID
FBal0258460
Feature type
allele
Associated gene
Dmel\dsx
Associated Insertion(s)
P+PBac{XP3.WH3}dsxf00683-d07058
Carried in Construct
Also Known As
dsx683-7058, Df(3R)f00683-d07058, dsx683
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Chatterjee et al., 2011)
Mutagen
FLPase
(Chatterjee et al., 2011)
Progenitor genotype
PBac{WH}dsxf00683
(Chatterjee et al., 2011)
P{XP}d07058
(Chatterjee et al., 2011)
Associated Insertion(s)
P+PBac{XP3.WH3}dsxf00683-d07058
Cytology
Description

FLPase-mediated recombination between the two progenitor insertions (PBac{WH}dsxf00683 and P{XP}d07058) results in a deletion which eliminates all dsx coding sequences. Neighbouring genes are intact.

(Chatterjee et al., 2011)
Allele components
Component
Use(s)
Inserted element
P+PBac{XP3.WH3}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:7,925,556..7,968,019 [-]
Comment:

Scer\FRT-mediated recombination between the two progenitor insertions has deleted the sequence between them, eliminating all dsx coding sequences.

(Chatterjee et al., 2011)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      dsx1/dsxf00683-d07058 males do not sing sine song and they sing less pulse song, with significant defects in inter-pulse interval, carrier frequency and amplitude, compared to heterozygous controls.

      dsxGAL4(DBD)::Zip-/dsxf00683-d07058 adult males have a similar number of doublesex TN1A neurons to dsxGAL4(DBD)::Zip-/+ controls; these neurons have a similar gross morphology and similar anterior arbor volume, but significantly reduced posterior arbor volume, compared to dsxGAL4(DBD)::Zip-/+ controls.

      (Shirangi et al., 2016)

      dsxf01649-d09625/dsxf00683-d07058 mutant animals do not have spermathecae or female accessory glands. All males have two accessory glands.

      dsxf00683-d07058/Df(3R)dsx15 mutant males develop two accessory glands.

      (Chatterjee et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Df(3R)f00683-d07058
      (Meissner et al., 2016, Shirangi et al., 2016, Chatterjee et al., 2011)
      dsx683-7058
      (Han et al., 2022, Han et al., 2022, Machado et al., 2017, Meissner et al., 2016, Luo and Baker, 2015)
      dsx683
      (Machado et al., 2017, Shirangi et al., 2016)
      dsxf00683-d07058
      Name Synonyms
      Secondary FlyBase IDs
        References (8)