A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Dmel\dar1Scer\UAS.cYa

General Information
SymbolDmel\dar1Scer\UAS.cYaSpeciesD. melanogaster
NameSaccharomyces cerevisiae construct a of YeFlyBase IDFBal0258678
Feature typealleleAssociated geneDmel\dar1
Allele class
Mutagenin vitro construct - regulatory fusion
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Description
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FB2013_03
FB2013_02
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Allele class
Mutagen
Mutations Mapped to the Genome
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
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Progenitor genotype
Nature of the lesion
Statement
Reference
Scer\UAS regulatory sequences drive expression of dar1 cDNA coding sequences.
Carried in construct
Cytology
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Statement
Reference
Overexpression of dar1[Scer\UAS.cYa] with the driver Scer\GAL4[477] causes dramatic overgrowth of dendrites in the class IV da neurons in early third-instar larvae. Similarly, the total dendritic length of these neurons is increased compared to controls. Sholl analysis shows that the increase in branch number and length takes place throughout the dendritic fields rather than being restricted to particular regions. No change in the size of dendritic fields or dendritic tiling is observed. Using the Flip-out technique, overexpression of dar1[Scer\UAS.cYa] in class IV da neuron or class I da neuron axons under the control of Scer\GAL4[477] does not significantly affect axon growth. Overexpression in class III da neurons increases the number of long curvy terminal branches.
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hide Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym
dar1Scer\UAS.cYa
 
Name Synonym
Saccharomyces cerevisiae construct a of Ye
 
Saccharyomyces cerevisiae construct a of Ye
 
Secondary FlyBase IDs
hide References ( 2 )
Research paper
Ye et al., 2011, J. Neurosci. 31(9): 3309--3319
Differential regulation of dendritic and axonal development by the novel kruppel-like factor dar1. [FBrf0213162]
FlyBase analysis
FlyBase, 1992-, FlyBase curation.
FlyBase curation. [FBrf0105495]