FlyBase Allele Report: Dmel\Naa20A[KK102646]

General Information

Symbol

Dmel\Naa20A^KK102646

Species

D. melanogaster

Name

FlyBase ID

FBal0259206

Feature type

allele

Associated gene

Dmel\Naa20A

Associated Insertion(s)

Carried in Construct

P{KK102646}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK102646}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK102646

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female fertile, with Scer\GAL4^bam.PU

(François et al., 2023)

lethal, with Scer\GAL4^αTub84B.PL

(François et al., 2023)

male fertile, with Scer\GAL4^nanos.PG

(François et al., 2023)

male fertile, with Scer\GAL4^NP1624

(François et al., 2023)

male sterile, with Scer\GAL4^bam.PU

(François et al., 2023)

Phenotype Manifest In

spermatozoon | absent, with Scer\GAL4^bam.PU

(François et al., 2023)

waste bag | absent, with Scer\GAL4^bam.PU

(François et al., 2023)

Detailed Description

Statement

Reference

Expression of NAA20^KK102646 under the control of Scer\GAL4^Act.PU in olfactory receptor neuron (ORN) clones does not cause defects in axon mistargeting or cell number in Or42a and Or59c-expressing ORNs.

(Stephan et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Naa20A^KK102646, Scer\GAL4^bam.PU has male sterile phenotype, suppressible by Ubr1^JF01341, Scer\GAL4^bam.PU

(François et al., 2023)

Naa20A^KK102646, Scer\GAL4^bam.PU has male sterile phenotype, suppressible by Hsap\NAA20^UASp.cFa, Scer\GAL4^bam.PU

(François et al., 2023)

NOT suppressed by

Statement

Reference

Naa20A^KK102646, Scer\GAL4^bam.PU has male sterile phenotype, non-suppressible by Naa20B^UASp.cFa, Scer\GAL4^bam.PU

(François et al., 2023)

Naa20A^KK102646, Scer\GAL4^bam.PU has male sterile phenotype, non-suppressible by CG31730^UASp.Tag:HA, Scer\GAL4^bam.PU

(François et al., 2023)

Naa20A^KK102646, Scer\GAL4^bam.PU has male sterile phenotype, non-suppressible by hyd^HMS00343, Scer\GAL4^bam.PU

(François et al., 2023)

Naa20A^KK102646, Scer\GAL4^bam.PU has male sterile phenotype, non-suppressible by poe^HMS00739, Scer\GAL4^bam.PU

(François et al., 2023)

Naa20A^KK102646, Scer\GAL4^αTub84B.PL has lethal phenotype, non-suppressible by Ubr1^KK105716, Scer\GAL4^αTub84B.PL

(François et al., 2023)

NOT Enhancer of

Statement

Reference

Scer\GAL4^Act.PU/Naa20A^KK102646 is a non-enhancer | somatic clone of abnormal neuroanatomy | adult stage | somatic clone phenotype of psidin^IG978

(Stephan et al., 2012)

Scer\GAL4^Act.PU/Naa20A^KK102646 is a non-enhancer of abnormal neuroanatomy | adult stage | somatic clone phenotype of psidin¹

(Stephan et al., 2012)

Other

Statement

Reference

Naa20A^KK102646, Scer\GAL4^Act.PU, psidin^IG978 has abnormal neuroanatomy | somatic clone | adult stage phenotype

(Stephan et al., 2012)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Naa20A^KK102646, Scer\GAL4^bam.PU has waste bag | absent phenotype, non-enhanceable by Ubr1^JF01341, Scer\GAL4^bam.PU

(François et al., 2023)

Suppressed by

Statement

Reference

Naa20A^KK102646, Scer\GAL4^bam.PU has spermatozoon | absent phenotype, suppressible | partially by Ubr1^JF01341, Scer\GAL4^bam.PU

(François et al., 2023)

Naa20A^KK102646, Scer\GAL4^bam.PU has spermatozoon | absent phenotype, suppressible by Hsap\NAA20^UASp.cFa, Scer\GAL4^bam.PU

(François et al., 2023)

Naa20A^KK102646, Scer\GAL4^bam.PU has waste bag | absent phenotype, suppressible by Hsap\NAA20^UASp.cFa, Scer\GAL4^bam.PU

(François et al., 2023)

NOT suppressed by

Statement

Reference

Naa20A^KK102646, Scer\GAL4^bam.PU has waste bag | absent phenotype, non-suppressible by Ubr1^JF01341, Scer\GAL4^bam.PU

(François et al., 2023)

NOT Enhancer of

Statement

Reference

Scer\GAL4^Act.PU/Naa20A^KK102646 is a non-enhancer | somatic clone of adult olfactory receptor neuron Or42a | somatic clone phenotype of psidin^IG978

(Stephan et al., 2012)

Scer\GAL4^Act.PU/Naa20A^KK102646 is a non-enhancer | somatic clone of adult olfactory receptor neuron Or59c | somatic clone phenotype of psidin^IG978

(Stephan et al., 2012)

Scer\GAL4^Act.PU/Naa20A^KK102646 is a non-enhancer of adult olfactory receptor neuron Or42a | somatic clone phenotype of psidin¹

(Stephan et al., 2012)

Scer\GAL4^Act.PU/Naa20A^KK102646 is a non-enhancer of adult olfactory receptor neuron Or59c | somatic clone phenotype of psidin¹

(Stephan et al., 2012)

Other

Statement

Reference

Naa20A^KK102646, Scer\GAL4^Act.PU, psidin^IG978 has adult olfactory receptor neuron Or42a | somatic clone phenotype

(Stephan et al., 2012)

Naa20A^KK102646, Scer\GAL4^Act.PU, psidin^IG978 has adult olfactory receptor neuron Or59c | somatic clone phenotype

(Stephan et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of NAA20^KK102646 under the control of Scer\GAL4^Act.PU in psidin^IG978 olfactory receptor neuron (ORN) clones results in a significant decrease in cell number of Or42a and Or59c-expressing ORNs. The axon mistargeting seen in Or42a and Or59c ORNs homozygous for psidin^IG978 is not enhanced by expression of NAA20^KK102646 under the control of Scer\GAL4^Act.PU.

Expression of NAA20^KK102646 under the control of Scer\GAL4^Act.PU does not enhance the reduction in cell number and axon mistargeting defects seen in Or42a and Or59c ORNs homozygous for psidin¹.

(Stephan et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Naa20A^KK102646 is rescued by Scer\GAL4^bam.PU/Naa20A^UASp.cFa

(François et al., 2023)

Partially rescued by

Naa20A^KK102646 is partially rescued by Naa20A^FN.UASp/Scer\GAL4^bam.PU

(François et al., 2023)

Naa20A^KK102646 is partially rescued by Scer\GAL4^bam.PU/Naa20A^RG.UASp