Open Close
General Information
Symbol
Dmel\twzKK107922
Species
D. melanogaster
Name
FlyBase ID
FBal0259576
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Male flies expressing twzKK107922 via Scer\GAL4Tdc2.PC at 29[o]C have only 0.33-fold of the normal twz RNA expression levels and only 0.42-fold of normal TfAP-2 expression. That is, expression of twzKK107922 reduces the level of both twz and TfAP-2.

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Scer\GAL4Tdc2.PC twzKK107922 males show similar high intensity fighting behaviours, but increased low intensity fighting compared to controls in male aggression assays.

Scer\GAL4Tdc2.PC twzKK107922 males show an increased frequency of mating behaviours towards other males or towards virgin females compared to controls.

Scer\GAL4Tdc2.PC twzKK107922 males do not show any change in their overall activity, though they walk at a significantly slower pace compared to controls.

Scer\GAL4Tdc2.PC twzKK107922 male flies over-eat after starvation compared to controls.

Scer\GAL4Tdc2.PC twzKK107922 male flies eat significantly more food ad lib than controls in a 24 hr period. The number of feeding bouts is unaffected, while meal size is slightly increased.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of twzKK107922 rescues the increased high intensity fighting and hyperactive phenotype of Scer\GAL4Tdc2.PC TfAP-2B.Scer\UAS male flies.

Co-expression of twzKK107922 suppresses the over-eating phenotypes seen in Scer\GAL4Tdc2.PC TfAP-2B.Scer\UAS male flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CG10440KK107922
twzKK107922
Name Synonyms
Secondary FlyBase IDs
    References (3)