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General Information
Symbol
Dmel\MCUKK108726
Species
D. melanogaster
Name
FlyBase ID
FBal0259720
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of MCUKK108726 driven by Scer\GAL4Act.PU or Scer\GAL4tub.PU results in lethality before adulthood.

Expression of MCUKK108726 (together with UAS-Dicer2, to enhance RNAi efficiency) driven by Scer\GAL4nSyb.PS or Scer\GAL4238Y, but not when driven by Scer\GAL4VT064246, Scer\GAL4ple.PF, Scer\GAL4GH146, Scer\GAL4Mz604, Scer\GAL4NP2492, Scer\GAL4NP2631, Scer\GAL4G0431, Scer\GAL4Orco.2.642.Hsim\VP22, Scer\GAL4c305a, Scer\GAL4GMR35B12, Scer\GAL4c739, Scer\GAL4GMR28H05, Scer\GAL4GMR16A06, or Scer\GAL4GMR11D09, impairs adult olfactory intermediate-term memory in olfactory aversive tests, as compared to controls.

Expression of MCUKK108726, with UAS-Dicer2 to enhance RNAi efficiency, driven by Scer\GAL4GMR13F02 or Scer\GAL4Tab2-201Y impairs intermediate-term memory in olfactory aversive tests (but not olfactory avoidance, shock avoidance, learning, or immediate or long-term memory) as compared to controls; the impairment persists after either anesthesia-sensitive memory elimination by cold-shock treatment or 5-times massed training.

Expression of MCUKK108726, with UAS-Dicer2 to enhance RNAi efficiency, driven by Scer\GAL4GMR13F02 or Scer\GAL4Tab2-201Y and temporally-limited by Gal80[ts] to pupation or pre-adulthood developing stages by Gal80[ts], respectively, impairs adult olfactory intermediate-term memory in olfactory aversive tests as compared to controls.

Expression of MCUKK108726, with UAS-Dicer2 to enhance RNAi efficiency, driven by Scer\GAL4GMR13F02 results in axons of adult mushroom body α and β neurons being longer and bigger, but with similar number of nodes, as compared to controls; mushroom body γ neurons appear unaltered.

Expression of MCUKK108726, with UAS-Dicer2 to enhance RNAi efficiency, driven by Scer\GAL4GMR16A06 does not impair adult intermediate-term olfactory memory.

Expression of MCUKK108726, with UAS-Dicer2 to enhance RNAi efficiency, driven by Scer\GAL4GMR25H11 impairs adult olfactory intermediate-term memory in olfactory aversive tests (but not odor avoidance or shock avoidance) as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CG18769KK108726
MCUKK108726
Name Synonyms
Secondary FlyBase IDs
    References (3)