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General Information
Symbol
Dmel\MadKK109050
Species
D. melanogaster
Name
FlyBase ID
FBal0259766
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-madRNAi, UAS-mad RNAi
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of MadKK109050 under the control of Scer\GAL4Bx-MS1096 results in male flies with almost complete wing loss.

Expression of MadKK109050 under the control of Scer\GAL4Bx-MS1096 results in female flies with severe wing size and patterning defects.

Expression of MadKK109050 (co-expressed with Dcr-2Scer\UAS.cDa) under the control of Scer\GAL4repo.PU reduces glial cell numbers in the third instar larval eye disc.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of MadKK109050 does not suppress the growth of the massive wing disc tumors seen when EgfrScer\UAS.cBa and psqKK111691 are expressed under the control of Scer\GAL4ap-md544. Apicobasal polarity and tissue organisation is restored to the epithelial cells.

Co-expression of MadKK109050 and MedJF02218 under the control of Scer\GAL4P2.4.Pdf reduces the strength of locomotor rhythmicity and induces strong arrhythmicity.

Expression of MadKK109050 suppresses the increase in glial cell number seen in larval eye discs expressing ykiS168A.Scer\UAS.T:SV5\V5 under the control of Scer\GAL4repo.PU.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
MadKK109050
Name Synonyms
Secondary FlyBase IDs
    References (6)