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General Information
Symbol
Dmel\Rbfox1KK109100
Species
D. melanogaster
Name
FlyBase ID
FBal0259771
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASt regulatory sequences drive expression of an inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Ectopic expression of Rbfox1KK109100 RNAi (together with UAS-Dcr2 to enhance RNAi efficiency) under the control of Scer\GAL4GMR13F02 decreases 3 hr memory in an aversive olfactory memory assay in adults compared to controls without altering odor or shock avoidance.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
The increased 3 hr memory in an aversive olfactory assay characteristic for adult expressing mir-980sponge.V2.Scer\UAS.T:Disc\RFP-mCherry under the control of Scer\GAL4elav-C155 is fully suppressed by co-expression of Rbfox1KK109100 RNAi. The memory index measured in flies expressing both transgenes is comparable to that observed in flies expressing Rbfox1KK109100 alone and below the control levels, indicating that mir-980 is epistatic to Rbfox1 in memory control.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
A2bp1KK109100
Rbfox1KK109100
Name Synonyms
Secondary FlyBase IDs
    References (3)