Expression of CdsANIG.7962R in both the larval fat body and salivary gland, under the control of Scer\GAL4ppl.PP, causes an ectopic lipid droplet phenotype.
Expression of CdsANIG.7962R under the control of Scer\GAL4αTub84B.PL, results in these larvae accumulating excess fat in many non-adipose tissues, including the salivary gland, proventriculus, hind gut, Malpighian tubules, and trachea. Compared to controls, Scer\GAL4αTub84B.PL-->CdsANIG.7962R animals exhibit a much higher level of triacylglycerol.
Expression of CdsANIG.7962R under the control of Scer\GAL4αTub84B.PL results in a significant reduction in organ size, compared to controls. The imaginal discs, salivary glands, and brain are smaller in these flies, compared to controls. While cell number is not changed in these mutants, cell size is greatly reduced.
The levels of diacylglycerol and phosphatidylethanolamine are significantly increased in fat body cells expressing CdsANIG.7962R under the control of Scer\GAL4αTub84B.PL.