FB2025_01 , released February 20, 2025
Allele: Dmel\caspPBacG75α
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General Information
Symbol
Dmel\caspPBacG75α
Species
D. melanogaster
Name
FlyBase ID
FBal0260911
Feature type
allele
Associated gene
Dmel\casp
Associated Insertion(s)
PBac{3xP3-EYFP,p-tTA-K10}caspPBacG75α
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    PBac{3xP3-EYFP,p-tTA-K10}caspPBacG75α
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        caspPBacG75α is a suppressor of abnormal mitotic cell cycle phenotype of Iswi2

        (Arancio et al., 2010)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        caspPBacG75α suppresses the shortening of the S phase, but not the G[[2]]/M increase which is seen in Iswi2 larval brain neuroblast cell populations.

        caspPBacG75α suppresses the pre-G1 defects seen in Iswi2 imaginal disc cell populations, restoring a cell cycle profile similar to wild type.

        (Arancio et al., 2010)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        caspPBacG75α
        (Arancio et al., 2010)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)