FB2025_01 , released February 20, 2025
Allele: Dmel\CG10527KG05615
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General Information
Symbol
Dmel\CG10527KG05615
Species
D. melanogaster
Name
FlyBase ID
FBal0260947
Feature type
allele
Associated gene
Dmel\CG10527
Associated Insertion(s)
P{SUPor-P}CG10527KG05615
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - molecular evidence

    (Burtenshaw et al., 2008)
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{SUPor-P}CG10527KG05615
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{SUPor-P}
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutants appear to show elevated methyl farnesoate (MF) levels in corpus allatum extracts compared to controls in the presence/absence of exogenous Ast protein. As for controls, addition of Ast does not affect MF release.

        In contrast to controls, addition of exogenous Ast significantly reduces Juvenile Hormone III levels, while it has no effect on Juvenile Hormone bisepoxide levels in mutant corpus allatum extracts.

        CG10527KG05615 homozygotes, CG10527KG05615/Df(2R)Pu-D17 animals or CG10527KG05615/Df(2R)PI13 animals all show reduced lifespan compared to controls.

        (Burtenshaw et al., 2008)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        13905
        (Burtenshaw et al., 2008)
        CG10527KG05615
        Name Synonyms
        Secondary FlyBase IDs
          References (1)