Open Close
General Information
Symbol
Dmel\upd1NIG.5993R
Species
D. melanogaster
Name
FlyBase ID
FBal0260957
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an upd1 RNAi construct.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of upd1NIG.5993R under the control of either Scer\GAL4tim.PE or Scer\GAL4mir-279.PC results in defects in locomotor activity rhythms (only 21.4% and 42.9% of flies respectively show rhythmic behaviour under constant darkness conditions).

Expression of upd1NIG.5993R under the control of two copies of Scer\GAL4tim.Scer\UAS results in defects in locomotor activity rhythms (only 42.1% of flies show rhythmic behaviour under constant darkness conditions).

Expression of upd1NIG.5993R under the control of two copies of Scer\GAL4P2.4.Pdf does not disrupt locomotor activity rhythms.

Expression of upd1NIG.5993R under the control of Scer\GAL4Mef2.247.Switch specifically during the adult stage (in the presence of RU486) causes a defect in long term memory, without affecting anesthesia-resistant memory or short term memory.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
NOT Suppressor of
Phenotype Manifest In
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

The locomotor rhythm defects seen in mir-279ex117-1 flies under constant darkness conditions are suppressed by expression of upd1NIG.5993R under the control of Scer\GAL4tim.Scer\UAS.

Expression of upd1NIG.5993R does not suppress the increase in circulating lamellocytes seen when ND-75GD6309 is expressed under the control of Scer\GAL4Antp-10.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
osNIG.5993R
upd1NIG.5993R
Name Synonyms
Secondary FlyBase IDs
    References (3)