Third instar Cip41/Df(3L)ED4342 larvae show an increase in bouton number/muscle area and satellite bouton number at the neuromuscular junction compared to wild type.
Cip41 homozygotes and Cip41/Df(3L)ED4342 trans-heterozygotes are semi-lethal at the pupal stage with an incidence of lethality of ~17%.
Cip41 mutant larvae exhibit an increase in bouton number, satellite bouton number and neuromuscular junction length.
Compared with wild-type controls, Cip41/Df(3L)ED4342 trans-heterozygous mutant larvae exhibit an increase in bouton number normalized to muscle surface area of approximately 32%. In addition, satellite bouton number and neuromuscular junction length normalized to muscle surface area are increased by 67% and 24%, respectively.
Cip41 heterozygous neuromuscular junctions do not exhibit any morphological changes.