FlyBase Allele Report: Dmel\Bub1[GL00151]

FB2025_01 , released February 20, 2025

FB2025_01 , released February 20, 2025

Allele: Dmel\Bub1^GL00151

General Information

Symbol

Dmel\Bub1^GL00151

Species

D. melanogaster

Name

FlyBase ID

FBal0262629

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{TRiP.GL00151}

Also Known As

GL00151

Key Links

Genomic Maps

Transgenic product class

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

(Ni et al., 2011.7.19)

Progenitor genotype

Carried in construct

P{TRiP.GL00151}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female semi-sterile, with Scer\GAL4^{VP16.nanos.UTR}, Scer\GAL4^VP16.otu, Scer\GAL4^nanos.PG

(Sopko et al., 2014)

fertile, with Scer\GAL4^{VP16.mat.αTub67C}

(Wang et al., 2021)

viable, with Scer\GAL4^{VP16.mat.αTub67C}

(Wang et al., 2021)

Phenotype Manifest In

chromosome, centromeric region | oogenesis, with Scer\GAL4^unspecified

(Joshi et al., 2024)

oocyte, with Scer\GAL4^unspecified

(Joshi et al., 2024)

Detailed Description

Statement

Reference

Females heterozygous for Bub1^GL00151 and MTD-Gal4 (consists of Scer\GAL4^{otu.T:Hsim\VP16}, Scer\GAL4^nos.PG and Scer\GAL4^{nos.UTR.T:Hsim\VP16}) crossed to Bub1^GL00151 males results in: 90% hatching; non-maternal effect.

(Sopko et al., 2014)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Bub1^GL00151, Haspin^GL00176, Scer\GAL4^{VP16.mat.αTub67C} has fertile phenotype

(Wang et al., 2021)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

35260

y¹ sc^* v¹ sev²¹; P{TRiP.GL00151}attP2

GL00151

y¹ sc^* v¹ sev²¹; P{TRiP.GL00151}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Bub1^GL00151

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections