Open Close
General Information
Symbol
Dmel\TorGL00156
Species
D. melanogaster
Name
FlyBase ID
FBal0262633
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
GL00156, UAS-Tor-shRNA
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of a short inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expressing TorGL00156 under the control of Scer\GAL4en.PU leads to more cells undergoing S-phase and mitosis in the posterior compartment of the wing disc (where Scer\GAL4en.PU is driving expression), despite a significant decrease in wing compartment size, as compared to controls.
Expression of TorGL00156 under the control of Scer\GAL4Myo31DF-NP0001 results in premature autophagy in the larval midgut and shortened gastric caeca at an early age, 4 hrs before puparium formation. Expression of TorGL00156 under the control of Scer\GAL4cg.PU results in a lack of autophagic difference in the larval fat body between fed and starved flies as compared to controls.
Females heterozygous for TorGL00156 and MTD-Gal4 (consists of Scer\GAL4otu.T:Hsim\VP16, Scer\GAL4nos.PG and Scer\GAL4nos.UTR.T:Hsim\VP16) crossed to TorGL00156 males results in: no eggs; egg/embryonic phenotype: no vitellogenic egg chambers; oogenesis defect.
Scer\GAL4He.PZ-mediated expression of TorGL00156 markedly downregulates hemocyte counts in larvae.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
The dramatic increase in apoptosis (visualized by [*]Casp3 or acridine orange staining) along with the elevated oxidative stress (monitored by levels of ROS) and increased frequency of aneuploid metaphases observed in larval wing discs upon expression of vtdGL00522 driven by Scer\GAL4en-e16E can be suppressed by co-expression of TorGL00156.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
TorGL00156
Name Synonyms
Secondary FlyBase IDs
    References (13)