FlyBase Allele Report: Dmel\par-1[GL00253]

General Information

Symbol

Dmel\par-1^GL00253

Species

D. melanogaster

Name

FlyBase ID

FBal0262723

Feature type

allele

Associated gene

Dmel\par-1

Associated Insertion(s)

Carried in Construct

P{TRiP.GL00253}

Also Known As

GL00253

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

(Ni et al., 2011.7.19)

Progenitor genotype

Carried in construct

P{TRiP.GL00253}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-GL00253

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile, with Scer\GAL4^{VP16.nanos.UTR}, Scer\GAL4^VP16.otu, Scer\GAL4^nanos.PG

(Sopko et al., 2014)

melanotic mass phenotype, with Scer\GAL4^{SPARC-MI00329-GAL4}

(Zang et al., 2015)

Phenotype Manifest In

dendritic microtubule, with Scer\GAL4⁴⁷⁷

(Bu et al., 2022)

embryo | maternal effect, with Scer\GAL4^{VP16.nanos.UTR}, Scer\GAL4^VP16.otu, Scer\GAL4^nanos.PG

(Sopko et al., 2014)

fat body, with Scer\GAL4^{SPARC-MI00329-GAL4}

(Zang et al., 2015)

larval dorsal multidendritic neuron ddaC, with Scer\GAL4⁴⁷⁷

(Bu et al., 2022)

melanotic mass, with Scer\GAL4^{SPARC-MI00329-GAL4}

(Zang et al., 2015)

Detailed Description

Statement

Reference

Expression of par-1^GL00253 under the control of Scer\GAL4^{SPARC-MI00329-GAL4} results in melanisation of the fat body.

(Zang et al., 2015)

Females heterozygous for par-1^GL00253 and MTD-Gal4 (consists of Scer\GAL4^{otu.T:Hsim\VP16}, Scer\GAL4^nos.PG and Scer\GAL4^{nos.UTR.T:Hsim\VP16}) crossed to par-1^GL00253 males results in: "few eggs,0% hatching"; egg/embryonic phenotype: few eggs and tiny; maternal effect; oogenesis defect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^ppk.PU/par-1^GL00253 is a suppressor of microtubule phenotype of Scer\GAL4^ppk.PU, chb^GL00367

(Bu et al., 2022)

Scer\GAL4^ppk.PU/par-1^GL00253 is a suppressor of larval dorsal multidendritic neuron ddaC phenotype of Scer\GAL4^ppk.PU, chb^GL00367

(Bu et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

35342

y¹ sc^* v¹ sev²¹; P{TRiP.GL00253}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

par-1^GL00253

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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