FB2025_01 , released February 20, 2025
Allele: Dmel\wtsHMS00026
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General Information
Symbol
Dmel\wtsHMS00026
Species
D. melanogaster
Name
FlyBase ID
FBal0263073
Feature type
allele
Associated gene
Dmel\wts
Associated Insertion(s)
Carried in Construct
P{TRiP.HMS00026}
Also Known As
wtsRNAi, UAS-wts-RNAi, UAS-wts RNAi, HMS00026, wts-IR
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2011.7.19)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2011.7.19)
Mutagen
in vitro construct
(Ni et al., 2011.7.19)
Progenitor genotype
Carried in construct
P{TRiP.HMS00026}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HMS00026
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      wtsHMS00026 expression driven by Scer\GAL4insc-Mz1407 does not result in obvious signs of quiescence in the larval brain, as neuroblasts show the expected rounded morphology and do not show changes in cell division (both DNA replication/EdU staining and Mitosis/phospho-H3), as compared to controls.

      (Ly et al., 2019)

      Expressing wtsHMS00026 under the control of Scer\GAL4Cg.PA leads to tubular mitochondria in the third instar larval fat body (as assessed by MitoGFP).

      (Zhou et al., 2019)

      Females heterozygous for wtsHMS00026 and MTD-Gal4 (consists of Scer\GAL4otu.T:Hsim\VP16, Scer\GAL4nos.PG and Scer\GAL4nos.UTR.T:Hsim\VP16) crossed to wtsHMS00026 males results in: 95% hatching; non-maternal effect.

      (Sopko et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      wtsHMS00026, Scer\GAL4Bx-MS1096 is a non-suppressor of abnormal size phenotype of Hsap\LATS1R806P.UAS, Scer\GAL4Bx-MS1096

      (Yu et al., 2013)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      wtsHMS00026
      (Forest et al., 2018)
      wtsRNAi
      (Ly et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (24)