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General Information
Symbol
Dmel\raptorHMS00124
Species
D. melanogaster
Name
FlyBase ID
FBal0263126
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Raptor RNAi, HMS00124, UAS-RaptorRNAi
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of a short inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Posterior dorsocentral bristle neurons expressing raptorHMS00124 under the control of Scer\GAL4pnr-MD237 show a significantly decreased terminal arbor territory and significantly fewer synapses (Syt1 puncta) on the contralateral collateral branch, as compared to controls.
Expression of raptorHMS00124 in cardiac muscle under the control of Scer\GAL4GMR88D05 has no effect on pupal eclosion rates. Expression of raptorHMS00124 in skeletal muscle under the control of Scer\GAL4how-24B results in lethality. Expression of raptorHMS00124 under the control of Scer\GAL4c179 causes partial lethality. The number of pupae formed does not differ from controls. Many of the surviving flies have a reduced climbing rate compared with controls. Expression of raptorHMS00124 under the control of Scer\GAL4Mhc.F3-580 has no effect on pupal eclosion rates and the adult flies do not exhibit any significant climbing defects. Lifespan is reduced compared with controls.
Females heterozygous for raptorHMS00124 and MTD-Gal4 (consists of Scer\GAL4otu.T:Hsim\VP16, Scer\GAL4nos.PG and Scer\GAL4nos.UTR.T:Hsim\VP16) crossed to raptorHMS00124 males results in: no eggs; egg/embryonic phenotype: no vitellogenic egg chambers; oogenesis defect.
Scer\GAL4nos.UTR.T:Hsim\VP16-mediated expression of raptorHMS00124 results in a block to oogenesis with females containing extremely small ovaries.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
raptorHMS00124
Name Synonyms
Secondary FlyBase IDs
    References (14)