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General Information
Symbol
Dmel\Sf3a1HMS00157
Species
D. melanogaster
Name
FlyBase ID
FBal0263153
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing Sf3a1HMS00157 under the control of Scer\GAL4Cg.PA leads to fragmented mitochondria in the third instar larval fat body (as assessed by MitoGFP).

The expression of Sf3a1HMS00157 under the control of Scer\GAL4SPARC-MI00329-GAL4 (and Dicer-2, for a more efficient RNAi) in the larval fat body induces defective secretion, including intracellular matrix material, as shown by the retention of both secr.GFP and Vkg.GFP.

The expression of Sf3a1HMS00157 under the control of Scer\GAL4insc-Mz1407 is embryonic lethal. Expression under the control of Scer\GAL4ase.neuro leads to a severe decrease in the number of type I neuroblast lineage cells.

Expression of CG16941HMS00157 driven by Scer\GAL4bam.T:Hsim\VP16 leads to complete male sterility, along with defects in spermatogonial differentiation and absence of mature sperm.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Supplemental Dataset_S01.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CG16941HMS00157
Sf3a1HMS00157
Name Synonyms
Secondary FlyBase IDs
    References (6)