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General Information
Symbol
Dmel\rlHMS00173
Species
D. melanogaster
Name
FlyBase ID
FBal0263168
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of a short inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Posterior dorsocentral bristle neurons expressing rlHMS00173 under the control of Scer\GAL4pnr-MD237 do not show obvious projection defects compared to controls.
Clones expressing rlHMS00173 (using P{CoinFLP-GAL4} and Scer\FLP1ey.PN to stochastically generate patches of cells expressing Scer\GAL4Act5C.CoinFLP-FRT) are eliminated from the adult eye and overall eye size is reduced. Expression of rlHMS00173 using P{AyGAL4} and Scer\FLP1ey.PN to generate clones in the eye expressing Scer\GAL4Act5C.PI results in near-complete loss of the adult eye.
Expressing rlHMS00173 under the control of Scer\GAL4ptc-559.1 results in loss of wing vein material in the anterior crossvein. Expressing rlHMS00173 under the control of either Scer\GAL4dpp.blk1 or Scer\GAL4ptc-559.1 has no effect on cell death in wing discs.
Females heterozygous for rlHMS00173 and MTD-Gal4 (consists of Scer\GAL4otu.T:Hsim\VP16, Scer\GAL4nos.PG and Scer\GAL4nos.UTR.T:Hsim\VP16) crossed to rlHMS00173 males results in: 0% hatching; egg/embryonic phenotype: fusion of denticles in ventral midline; maternal effect.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Suppressor of
Phenotype Manifest In
Suppressor of
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
The expression of Dsor1HMS00145 under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 does not suppress the decreased primordial germ cells in rlHMS00173 homozygous early embryos (i.e. mitotic cycles 12/13).
Expression of rlHMS00173 partially suppresses the cardiac hypertrophy seen when ykiS168A.Scer\UAS.T:SV5\V5 is expressed under the control of Scer\GAL4tin.CΔ4.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
rlHMS00173
Name Synonyms
Secondary FlyBase IDs
    References (10)