FB2019_05, released Oct 15, 2019

Allele: Dmel\LarHMS00822

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General Information
Symbol
Dmel\LarHMS00822
Species
D. melanogaster
Name
FlyBase ID
FBal0263220
Feature type
allele
Associated gene
Dmel\Lar
Associated Insertion(s)
Carried in Construct
P{TRiP.HMS00822}
Genomic Maps
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - RNAi
(Ni et al., 2011.7.19)
in vitro construct - regulatory fusion
(Ni et al., 2011.7.19)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{TRiP.HMS00822}
      Cytology
      Nature of the lesion
      Statement
      Reference
      UAS regulatory sequences drive expression of a short inverted repeat.
      (Ni et al., 2011.7.19)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UAS
      Encoded product / tool
      Lar
      Also carries
      loxP
      Associated Sequence Features
      dsRNA-HMS00822
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      Females heterozygous for LarHMS00822 and MTD-Gal4 (consists of Scer\GAL4otu.T:Hsim\VP16, Scer\GAL4nos.PG and Scer\GAL4nos.UTR.T:Hsim\VP16) crossed to LarHMS00822 males results in: 68% hatching; non-maternal effect.
      (Sopko et al., 2014)
      Expression of LarHMS00822 under the control of Scer\GAL4futsch-C380 suppresses the increase in "ghost bouton" number (axon terminal extensions with synaptic vesicles but lacking active zones and postsynaptic structures) per neuromuscular junction caused by spaced high K[+] depolarization.
      (Nesler et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      LarHMS00822
      Name Synonyms
      Secondary FlyBase IDs
        References (4)