Expression of Ras85DV12.Scer\UAS under the control of Scer\GAL4Act.PU in clones in the eye-antennal disc (where the clones are also homozygous for scrib673) results in strong tumour growth at 7 days AEL. These animals grow as larvae until 13 days AEL and die before pupation. Co-expression of sds22Scer\UAS.cJa in these clones strongly suppresses the tumour growth phenotype in all clones observed at 7 days AEL and most of these animals can pupate, but die as early pupae.
The eye-antennal disc defects seen in larvae carrying homozygous scrib673 clones and the eye defects seen in adult escapers carrying homozygous scrib673 clones are suppressed by expression of sds22Scer\UAS.cJa under the control of Scer\GAL4Act.PU in the clones.
Eye overgrowth caused by expression of Ras85DV12.Scer\UAS under the control of Scer\GAL4ey.PU is not suppressed by co-expression of sds22Scer\UAS.cJa.