FB2025_01 , released February 20, 2025
Allele: Mmus\Thoc5UAS.cMa
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General Information
Symbol
Mmus\Thoc5UAS.cMa
Species
M. musculus
Name
FlyBase ID
FBal0263668
Feature type
allele
Associated gene
Mmus\Thoc5
Associated Insertion(s)
Carried in Construct
P{UAS-mThoc5}
Transgenic product class
wild_type
(Moon et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Moon et al., 2011)
Mutagen
in vitro construct
(Moon et al., 2011)
Progenitor genotype
Carried in construct
P{UAS-mThoc5}
Cytology
Description

UAS regulatory sequences drive expression of Mmus\Thoc5.

(Moon et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Mmus\Thoc5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Mmus\Thoc5Scer\UAS.cMa under the control of Scer\GAL4da.G32 partially rescues the mutant testis phenotypes. Nucleolar structure is restored to normal. Chromosome condensation is much similar to wild-type, although chromosome shape appear somewhat abnormal. Elongating spermatid flagella are observed.

      (Moon et al., 2011)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Mmus\Thoc5Scer\UAS.cMa
      Mmus\Thoc5UAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Moon
      (Moon et al., 2011)
      Secondary FlyBase IDs
        References (1)