FB2025_01 , released February 20, 2025
Allele: Dmel\sdtB.UAS
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General Information
Symbol
Dmel\sdtB.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0263708
Feature type
allele
Associated gene
Dmel\sdt
Associated Insertion(s)
Carried in Construct
P{UAS-sdt.B}
Key Links
Transgenic product class
wild_type
(Horne-Badovinac and Bilder, 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Horne-Badovinac and Bilder, 2008)
Mutagen
in vitro construct
(Horne-Badovinac and Bilder, 2008)
Progenitor genotype
Carried in construct
P{UAS-sdt.B}
Cytology
Description

UAS regulatory and drive expression of a mutated form of sdt that lacks exon 3 (equivalent to the sdt-RF isoform).

(Horne-Badovinac and Bilder, 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
sdt
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4nanos.PG/sdtB.UAS partially rescues sdtEH681

      (Horne-Badovinac and Bilder, 2008)
      Comments

      Expression of sdtB.Scer\UAS under the control of the maternal driver Scer\GAL4nos.PG partially rescues the cuticle phenotype seen in sdtEH681 mutant embryos. 13% of embryos examined showed continuous cuticle over 2/3 of the surface compared to 8% in the negative control and approximately 10% only displayed cuticle fragments compared to over 70% in controls.

      (Horne-Badovinac and Bilder, 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sdtB.Scer\UAS
      sdtB.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)