Allele Dmel\Hr38^{dsRNA.Scer\UAS}

General Information
Symbol	Dmel\Hr38^{dsRNA.Scer\UAS}	Species	D. melanogaster
Name		FlyBase ID	FBal0263929
Feature type	allele	Associated gene	Dmel\Hr38

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - RNAi
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Sekine et al., 2011) in vitro construct - RNAi (Sekine et al., 2011)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS drives expression of a head-to-head inverted repeat of Hr38 cDNA (nt 1-139). (Sekine et al., 2011)
Carried in construct	P{UAS-Hr38.IR} (Sekine et al., 2011)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| heat sensitive, with Scer\GAL4^pnr-MD237 (Sekine et al., 2011)
Phenotype Manifest In

Detailed Description
	Statement Reference Scer\GAL4[pnr-MD237]-mediated expression of Hr38[dsRNA.Scer\UAS] is lethal if flies are maintained at 25[o]C but viable at 18[o]C. (Sekine et al., 2011)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference Hr38^{dsRNA.Scer\UAS}, Scer\GAL4^pnr-MD237 is a suppressor \| partially of body color defective phenotype of Pk92B^{ΔN.Scer\UAS.T:Zzzz\FLAG}, Scer\GAL4^pnr-MD237 (Sekine et al., 2011)
Phenotype Manifest In
Suppressor of
Statement Reference Hr38^{dsRNA.Scer\UAS}, Scer\GAL4^pnr-MD237 is a suppressor \| partially of adult thorax phenotype of Pk92B^{ΔN.Scer\UAS.T:Zzzz\FLAG}, Scer\GAL4^pnr-MD237 (Sekine et al., 2011)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Hr38^{dsRNA.Scer\UAS}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Sekine et al., 2011, J. Cell Sci. 124(17): 3006--3016 p38 MAPKs regulate the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors. [FBrf0215011]

Allele Dmel\Hr38dsRNA.Scer\UAS

Allele Dmel\Hr38^{dsRNA.Scer\UAS}