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General Information
Symbol
Dmel\mir-11Δ1
Species
D. melanogaster
Name
FlyBase ID
FBal0264143
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Deletion that specifically removes the mir-11 locus.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes show no obvious developmental defects when raised under normal conditions. The pattern of cell proliferation in clones in the eye disc appears normal, and no spontaneous apoptosis is seen in in these clones.

Homozygous larvae show reduced survival after irradiation compared to wild type.

Apoptosis following irradiation is detected earlier in homozygous clones in the eye disc (as early as 1 hour after irradiation) than in wild-type discs (apoptosis is first detected 2 hours following irradiation). Four hours after irradiation, the stripe of apoptosis seen anterior to the morphogenetic furrow is broadened in homozygous clones compared to wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)