FB2021_01, released Feb 18, 2021

Allele: Dmel\CkIIβdsRNA.cJa.UAS

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General Information
Symbol
Dmel\CkIIβdsRNA.cJa.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0264187
Feature type
allele
Associated gene
Dmel\CkIIβ
Associated Insertion(s)
Carried in Construct
P{UAS-CkIIβ.RNAi.J}
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - RNAi
(Jia et al., 2010)
in vitro construct - regulatory fusion
(Jia et al., 2010)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{UAS-CkIIβ.RNAi.J}
      Cytology
      Nature of the lesion
      Statement
      Reference

      UASt regulatory sequences drive expression of a genomic fragment containing nucleotides 91-239 CkIIβ coding sequence and the corresponding CkIIβ cDNA in reverse orientations.

      (Jia et al., 2010)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UASt
      Encoded product / tool
      CkIIβ
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of CkIIβdsRNA.cJa.Scer\UAS under the control of Scer\GAL4C-765 results in wings that are wild type in size but display ectopic wing veins between veins 2 and 3.

      Expression of CkIIβdsRNA.cJa.Scer\UAS under the control of Scer\GAL4ptc-559.1 produces a fused wing vein phenotype.

      (Jia et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of CkIIβdsRNA.cJa.Scer\UAS and smoPKA12.Scer\UAS under the control of Scer\GAL4C-765 results in flies that have small wings consisting of the anterior- and posterior-most wing structures.

      (Jia et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      CkIIβdsRNA.cJa.UAS is rescued by Scer\GAL4ptc-559.1/CkIIβUAS.Tag:FLAG

      (Jia et al., 2010)
      Comments

      Co-expression of CkIIβScer\UAS.T:Zzzz\FLAG rescues the wing vein phenotype seen when CkIIβdsRNA.cJa.Scer\UAS is expressed under the control of Scer\GAL4ptc-559.1.

      Co-expression of CkIIβScer\UAS.T:Zzzz\FLAG suppresses the small wing phenotype seen when CkIIβdsRNA.cJa.Scer\UAS and smoPKA12.Scer\UAS are expressed under the control of Scer\GAL4C-765.

      (Jia et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CkIIβdsRNA.cJa.Scer\UAS
      CkIIβdsRNA.cJa.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)