FB2025_01 , released February 20, 2025
Allele: Dmel\Gγ1NIG.8261R
Open Close
General Information
Symbol
Dmel\Gγ1NIG.8261R
Species
D. melanogaster
Name
FlyBase ID
FBal0264683
Feature type
allele
Associated gene
Dmel\Gγ1
Associated Insertion(s)
Carried in Construct
P{NIG.8261R}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Yao and Carlson, 2010)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Yao and Carlson, 2010)
Mutagen
in vitro construct
(Yao and Carlson, 2010)
Progenitor genotype
Carried in construct
P{NIG.8261R}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Yao and Carlson, 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-8261R
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      24 hours after UV-induced nociceptive sensitization, larvae with expression of Gγ1NIG.8261R driven by Scer\GAL4ppk.1.9 show significant reduction of thermal allodynia (withdrawal responses to a sub-threshold 38[o]C probe) compared to controls.

      (Im et al., 2015)

      Expression of Gγ1NIG.8261R under the control of Scer\GAL4Gr21a.9.323 does not reduce the response of the ab1C olfactory receptor neuron to CO[[2]].

      (Yao and Carlson, 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Gγ1NIG.8261R significantly partially suppresses the withdrawal responses to a 38[o]C probe (without pre-exposure to UV) seen in early third instar larvae with TkR99DScer\UAS.T:Avic\GFP-EGFP over-expressed by Scer\GAL4ppk.1.9.

      (Im et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Gγ1NIG.8261R
      Name Synonyms
      Secondary FlyBase IDs
        References (4)