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General Information
Symbol
Dmel\PGRP-LCx.UAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0264783
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of the 500aa isoform of PGRP-LC tagged at the C-terminal end with Tag:FLAG.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

At 25[o]C, Scer\GAL4Cg.PA-mediated expression of PGRP-LCx.Scer\UAS.T:Zzzz\FLAG is lethal. At 18[o]C, the structure of the larval fat body is strongly perturbed - cells round up and detach.

Expression of PGRP-LCx.Scer\UAS.T:Zzzz\FLAG under the control of either Scer\GAL4Cg.PA, Scer\GAL4Hml.PG or Scer\GAL4yolk results in IMD pathway activation in the absence of bacterial infection.

Expression of PGRP-LCx.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4Cg.PA results in melanization in larval, pupal and adult tissues in the absence of bacterial infection. No melanization is seen when PGRP-LCx.Scer\UAS.T:Zzzz\FLAG is expressed under the control of Scer\GAL4yolk.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
PGRP-LCx.Scer\UAS.T:Zzzz\FLAG
PGRP-LCx.UAS.Tag:FLAG
Name Synonyms
Secondary FlyBase IDs
    References (3)