FlyBase Allele Report: Dmel\hid[GMR.PG]

General Information

Symbol

Dmel\hid^GMR.PG

Species

D. melanogaster

Name

glass multimer reporter construct of Grether

FlyBase ID

FBal0265023

Feature type

allele

Associated gene

Dmel\hid

Associated Insertion(s)

Carried in Construct

P{GMR-hid.w^-}

P{GMR-hid}

Also Known As

GMR-hid, GMRhid, pGMR-hid, GMR>hid, P[GMR-hid], P^GMR-hid, GMR-hid¹⁰

Key Links

Transgenic product class

cDNA

(Grether et al., 1995)

wild_type

(Grether et al., 1995)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Grether et al., 1995)

wild_type

(Grether et al., 1995)

Mutagen

in vitro construct

(Chen et al., 1998, Grether et al., 1995)

Progenitor genotype

Carried in construct

P{GMR-hid.w^-}

P{GMR-hid}

Cytology

Description

Expression of 3.9kb EcoRI fragment containing the hid cDNA is driven by GMR regulatory sequences.

(Grether et al., 1995)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

hid

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior | larval stage | recessive

(Busto et al., 1999)

abnormal cell death

(Lisi et al., 2000, Bergmann et al., 1998)

abnormal locomotor behavior | larval stage

(Hassan et al., 2000)

abnormal locomotor rhythm

(Klarsfeld et al., 2004)

abnormal neuroanatomy

(Rodriguez Moncalvo and Campos, 2005, Malpel et al., 2002)

abnormal phototaxis | larval stage

(Hassan et al., 2000)

abnormal size

(Herz et al., 2009)

abnormal size | adult stage

(Velentzas et al., 2018, Chang et al., 2008, Nairz et al., 2006)

abnormal visual behavior

(Mazzoni et al., 2005)

decreased size | adult stage

(Das et al., 2023, Farrell et al., 2022, Nagel et al., 2021)

increased cell death

(Chakraborty et al., 2015, Christiansen et al., 2013, Morishita et al., 2013, Schoenherr et al., 2012, Gafuik and Steller, 2011, Sandu et al., 2010, Schreader et al., 2010, Lee et al., 2008, Chou et al., 2007, Herz et al., 2006, Lai et al., 2005, Rodriguez Moncalvo and Campos, 2005, Jia et al., 2003, Hays et al., 2002, Tapon et al., 2002, Taguchi et al., 2000, Kurada and White, 1998, Grether et al., 1995)

increased cell death, with Scer\GAL4^GMR.PF

(Louis et al., 2015)

increased cell death | larval stage

(Farrell et al., 2022, Srivastava et al., 2007)

increased cell death | third instar larval stage

(Wang et al., 2013, Kondo et al., 2006)

increased occurrence of cell division | larval stage

(Srivastava et al., 2007)

visible

(Wu et al., 2016, Chakraborty et al., 2015, Yang et al., 2014, Osterloh et al., 2012, Schoenherr et al., 2012, Hao et al., 2010, Schreader et al., 2010, Ribaya et al., 2009, Tiwari and Roy, 2009, Lee et al., 2008, Bilen and Bonini, 2007, Huh et al., 2007, Krieser et al., 2007, Pfleger et al., 2007, Kondo et al., 2006, Leulier et al., 2006, Xu et al., 2006, Müller et al., 2005, Daish et al., 2004, Gottfried et al., 2004, Rusconi et al., 2004, Bach et al., 2003, Brennecke et al., 2003, Ditzel et al., 2003, Hays et al., 2002, Higashiyama et al., 2002, Ryoo et al., 2002, Wilson et al., 2002, Wing et al., 2002, Harvey et al., 2001, Quinn et al., 2000, Taguchi et al., 2000, Kanuka et al., 1999, Rodriguez et al., 1999, Stowers and Schwarz, 1999, Bergmann et al., 1998, Kurada and White, 1998, Sawamoto et al., 1998, Grether et al., 1995)

visible, with Scer\GAL4^GMR.PF

(Louis et al., 2015)

visible | adult stage

(Das et al., 2023, Nagel et al., 2021, Velentzas et al., 2018, Neukomm et al., 2017, Koerver et al., 2016, Chang et al., 2008)

visible | dominant

(Lisi et al., 2000)

visible | somatic clone

(Xu et al., 2005)

Phenotype Manifest In

Bolwig nerve

(Malpel et al., 2002)

Bolwig organ

(Hassan et al., 2000)

eye

(Das et al., 2023, Nagel et al., 2021, Velentzas et al., 2018, Neukomm et al., 2017, Wu et al., 2016, Chakraborty et al., 2015, Head et al., 2015, Yang et al., 2014, Christiansen et al., 2013, Morishita et al., 2013, Domingues and Ryoo, 2012, Osterloh et al., 2012, Schoenherr et al., 2012, Hao et al., 2010, Sandu et al., 2010, Schreader et al., 2010, Galindo et al., 2009, Herz et al., 2009, Mallik and Lakhotia, 2009, Ribaya et al., 2009, Tiwari and Roy, 2009, Chang et al., 2008, Lee et al., 2008, Bilen and Bonini, 2007, Chou et al., 2007, Huh et al., 2007, Krieser et al., 2007, Pfleger et al., 2007, Srivastava et al., 2007, Fang et al., 2006, Herz et al., 2006, Kondo et al., 2006, Leulier et al., 2006, Muro et al., 2006, Xu et al., 2006, Lai et al., 2005, Müller et al., 2005, Wildonger et al., 2005, Daish et al., 2004, Gottfried et al., 2004, Bach et al., 2003, Brennecke et al., 2003, Ditzel et al., 2003, Quinn et al., 2003, Hays et al., 2002, Higashiyama et al., 2002, Ryoo et al., 2002, Tapon et al., 2002, Wilson et al., 2002, Wing et al., 2002, Harvey et al., 2001, Lisi et al., 2000, Meier et al., 2000, Quinn et al., 2000, Song et al., 2000, Taguchi et al., 2000, Kanuka et al., 1999, Rodriguez et al., 1999, Zhou et al., 1999, Bergmann et al., 1998, Kurada and White, 1998, Sawamoto et al., 1998, Grether et al., 1995, Hay et al., 1995)

eye, with Scer\GAL4^GMR.PF

(Louis et al., 2015)

eye | adult stage

(Farrell et al., 2022, Koerver et al., 2016)

eye | somatic clone

(Wang et al., 2008, Xu et al., 2005)

eye disc

(Schoenherr et al., 2012, Lee et al., 2008, Srivastava et al., 2007, Kondo et al., 2006, Rodriguez Moncalvo and Campos, 2005, Jia et al., 2003, Taguchi et al., 2000, Sawamoto et al., 1998)

eye disc | larval stage

(Farrell et al., 2022)

eye disc | third instar larval stage

(Wang et al., 2013)

eyelet

(Head et al., 2015)

interommatidial bristle

(Nairz et al., 2006)

larval LN period neuron

(Malpel et al., 2002)

ocellus

(Head et al., 2015)

ommatidium

(Nairz et al., 2006, Gottfried et al., 2004, Rusconi et al., 2004, Shi and Skeath, 2004, Hays et al., 2002, Rodriguez et al., 1999, Bergmann et al., 1998)

ommatidium | decreased number

(Das et al., 2023)

photoreceptor neuron

(Rodriguez Moncalvo and Campos, 2005, Stowers and Schwarz, 1999)

serotonergic neuron

(Rodriguez Moncalvo and Campos, 2005)

Detailed Description

Statement

Reference

hid^GMR.PG induces a small eye.

(Nagel et al., 2021, Velentzas et al., 2018)

Expression of hid^GMR.PG induces a widespread cell death in the developing visual system resulting in very small adult eyes.

(Neukomm et al., 2017)

Expression of hid^GMR.PG results in small and rough eye phenotype in adult flies.

(Koerver et al., 2016)

hid^GMR.PG flies have an eye ablation phenotype.

(Wu et al., 2016)

Flies expressing hid^GMR.PG have a reduced eye, due to increased cell death.

(Chakraborty et al., 2015)

hid^GMR.PG mutants exhibit normal light-dependent temperature preference. Similarly to wild-type, they prefer higher temperature in the light than in the dark.

(Head et al., 2015)

As in wild type, hid^GMR.PG mutant males exhibit inhibition of the female contact-induced male-male aggression seen in wild type males that have previously been exposed to females.

(Yuan et al., 2014)

W^GMR.PG animals display an eye-ablation phenotype as a result of massive apoptosis.

(Christiansen et al., 2013)

hid^GMR.PG induces apoptosis in imaginal eye discs of third instar larvae.

(Wang et al., 2013)

Early third instar larvae carrying W^GMR.PG show a normal avoidance response to a spot of intense light.

(Berni et al., 2012)

W^GMR.PG generates a small eye phenotype due to eye ablation.

(Domingues and Ryoo, 2012)

W^GMR.PG flies have a small eye.

W^GMR.PG third larval instar eye discs show increased apoptosis posterior to the second mitotic wave as well as in the posterior region of the eye disc within an additional region of cell division called the zone of compensatory proliferation.

(Schoenherr et al., 2012)

Flies expressing hid^GMR.PG show eye defects.

(Hao et al., 2010)

Flies carrying W^GMR.PG show ectopic cell death in the eye.

(Schreader et al., 2010)

W^GMR.PG eyes are ablated.

(Galindo et al., 2009)

W^GMR.PG adult flies have very small eyes.

(Herz et al., 2009)

Eyes are highly ablated and abnormally shaped.

(Mallik and Lakhotia, 2009)

Flies expressing W^GMR.PG have smaller eyes than normal.

(Ribaya et al., 2009)

Expression of W^GMR.PG under the control of Scer\GAL4^GMR.PF causes a dramatic reduction in adult eye size.

(Chang et al., 2008)

Flies carrying W^GMR.PG have a small eye phenotype, due to increased apoptotic cell death in the developing eye disc.

(Lee et al., 2008)

W^GMR.PG eye clones result in a small eye phenotype.

(Wang et al., 2008)

Expression of W^GMR.PG results in ablation of the eye.

(Bilen and Bonini, 2007)

hid^GMR.PG mutants exhibit a small, less-pigmented eye, due to apoptosis in the developing eye.

(Chou et al., 2007)

Flies expressing W^GMR.PG have a small rough eye.

(Krieser et al., 2007)

Flies carrying W^GMR.PG show almost complete ablation of the eye.

(Pfleger et al., 2007)

W^GMR.PG flies show a strong eye ablation phenotype.

W^GMR.PG eye imaginal discs exhibit increased caspase-3 staining, indicating apoptosis, overlapping with the second mitotic wave.

W^GMR.PG eye imaginal discs contain an additional zone of proliferating cells posterior to the second mitotic wave, termed the 'zone of compensatory proliferation' (ZCP). A zone of dying cells is present immediately behind this ZCP, which presumably eliminates the newly formed cells.

(Srivastava et al., 2007)

Flies expressing W^GMR.PG show a small eye phenotype.

(Fang et al., 2006)

W^GMR.PG causes a strong eye-ablation phenotype as a result of the induction of apoptosis.

(Herz et al., 2006)

Adults expressing W^GMR.PG show a dramatic reduction in eye size compared to wild type.

Expression of W^GMR.PG induces extensive apoptosis posterior to the morphogenetic furrow in third larval instar eye discs.

(Kondo et al., 2006)

Flies that express W^GMR.PG have small eyes.

(Muro et al., 2006)

Expression of the W^GMR.PG transgene in postmitotic cells of the eye disc leads to small, rough eyes.

(Nairz et al., 2006)

W^GMR.PG flies show an eye ablation phenotype.

(Xu et al., 2006)

W^GMR.PG larvae are blind.

(Mazzoni et al., 2005)

Ablation of the larval eye by expression of W^GMR.PG in all photoreceptors causes a significant reduction in the 5-HT arborization.

(Rodriguez Moncalvo and Campos, 2005)

Expression of W^GMR.PG in the eye reduces the overall size and pigmentation of the eye.

(Wildonger et al., 2005)

Mosaic animals in which the eyes are expressing W^GMR.PG have an eye ablation phenotype.

(Xu et al., 2005)

Flies carrying W^GMR.PG have rough and reduced eyes.

(Gottfried et al., 2004)

At high-light intensity, W^GMR.PG flies are able to resynchronize to a shift in the light-dark schedule of 8 hours. However, at 1000-fold lower light intensity, W^GMR.PG mutants take longer to synchronize to new schedules than wild-type flies. These mutants are unable to entrain to red light-dark schedules, to which wild-type flies can entrain.

Exposing W^GMR.PG flies to constant light results in arrhythmicity, as with wild-type flies.

(Klarsfeld et al., 2004)

Flies expressing W^GMR.PG have small, rough eyes.

(Rusconi et al., 2004)

Flies carrying W^GMR.PG have a smaller eye than normal (about two-thirds the size of wild type), which is rough and glassy in the posterior half.

(Bach et al., 2003)

Mutant animals have small rough eyes.

(Brennecke et al., 2003)

Expression of W^GMR.PG results in widespread ectopic apoptosis in the developing eye, resulting in mis-patterning of the ommatidial rows and a reduction in size of the adult eye field.

(Hays et al., 2002)

W^GMR.PG results in a dosage dependent eye degeneration phenotype.

(Higashiyama et al., 2002)

Third instar larvae expressing W^GMR.PG completely lack the Bolwig's nerve and the dendritic tree of the lateral neurons is extremely reduced (being undetectable in 72% cases). The developing adult photoreceptors are present in these larvae, but degenerate during the pupal stage.

(Malpel et al., 2002)

Flies expressing W^GMR.PG show an eye ablation phenotype.

(Ryoo et al., 2002)

Mutants have small eyes.

(Tapon et al., 2002)

Flies expressing W^GMR.PG have an ablated eye phenotype.

(Wilson et al., 2002)

Flies expressing W^GMR.PG have a severely ablated eye.

(Harvey et al., 2001)

Mutant larvae show significantly lower locomotion than control larvae and do not respond to light (as measured by a "checker assay"). Larval photoreceptors are either absent or severely damaged.

(Hassan et al., 2000)

Eye is small and roughened.

(Lisi et al., 2000)

Mutants have eyes that are severely reduced in size. The addition of Df(3L)AC1 to W^GMR.PG flies shows a significant suppression of the eye phenotype seen in these eyes.

(Meier et al., 2000)

Flies carrying W^GMR.PG have an ablated eye phenotype.

(Quinn et al., 2000)

W^GMR.PG flies have a mild but easily detectable eye phenotype.

(Song et al., 2000)

Flies carrying rpr^GMR.PW have a small eye phenotype and show increased numbers of dying cells posterior to the morphogenetic furrow.

(Taguchi et al., 2000)

Wild-type larvae reduce their path lengths when exposed to light. This response is reduced in larvae carrying W^GMR.PG. Wild-type larvae show increased head swinging when exposed to light. This response is abolished in larvae carrying W^GMR.PG. Wild-type larvae show a greater change in direction when lights are turned on or off (light (L) to dark (D), or D to L transition) than in the absence of a light transition (D to D). The amplitude of change of direction is greater for the D to L than for the L to D transition. This difference in the amplitude of change of direction between the D to L and L to D transitions is abolished in larvae carrying W^GMR.PG, although change of direction in the absence of a light transition (D to D) is still significantly lower than for either the D to L and L to D transition.

(Busto et al., 1999)

Two copies of W^GMR.PG in an otherwise wild-type background result in a severely roughened, small eye.

(Rodriguez et al., 1999)

Adult flies carrying one copy of W^GMR.PG lack photoreceptor cells.

(Stowers and Schwarz, 1999)

Eyes are severely reduced in size and devoid of most normal ommatidial morphology. The severity of the effect is dosage sensitive. Phenotypes of W^GMR.PG, W^Ala3.GMR and W^Ala5.GMR are comparable. Phenotype is slightly suppressed by hemizygosity at the endogenous W locus.

(Bergmann et al., 1998)

Cell-killing in the eye induced by W^GMR.PG is not noticeably affected by Df(1)su(s)R194.

(Chen et al., 1998)

Eye ablation due to apoptosis.

(Kurada and White, 1998)

Adult eye is dramatically reduced, almost ablated. In larval eye discs, increased numbers of cells are observed posterior to the morphogenetic furrow.

(Sawamoto et al., 1998)

Individuals carrying one copy of P{GMR-hid} display a dramatic eye ablation phenotype. In place of the compound eye is undifferentiated cuticle and a dense band of bristles (mechanosensory bristles normally found at the corner of each ommatidium). The eye phenotype can be completely suppressed by coexpression of BacA\p35.

(Grether et al., 1995)

Eyes are small.

(Hay et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Ret^GMR.PR, hid^GMR.PG has visible phenotype, enhanceable by Fak^UAS.Tag:HA/Scer\GAL4^GMR.PU

(Macagno et al., 2014)

hid^GMR.PG has visible phenotype, enhanceable by CG8830[+]/DUBAI^KG07439

(Yang et al., 2014)

hid^GMR.PG has visible phenotype, enhanceable by DUBAI^GD14040/Scer\GAL4^GMR.PFa

(Yang et al., 2014)

hid^GMR.PG has visible | adult stage phenotype, enhanceable by NetB^Δ

(Newquist et al., 2013)

hid^GMR.PG has visible phenotype, enhanceable by Ack⁸⁶/Ack⁸⁶

(Schoenherr et al., 2012)

hid^GMR.PG has visible phenotype, enhanceable by Ack^GD8506/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has visible phenotype, enhanceable by Rab11^mo

(Tiwari and Roy, 2009)

hid^GMR.PG has visible phenotype, enhanceable by Acox1^B227.2/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has visible phenotype, enhanceable by emb^E2-1A/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has visible phenotype, enhanceable by PSR[+]/JMJD6^FM1

(Krieser et al., 2007)

hid^GMR.PG has visible phenotype, enhanceable by JMJD6^FM1/JMJD6^FM1

(Krieser et al., 2007)

hid^GMR.PG has abnormal locomotor rhythm phenotype, enhanceable by cry^b

(Klarsfeld et al., 2004)

hid^GMR.PG has visible phenotype, enhanceable by D^unspecified

(Bach et al., 2003)

hid^GMR.PG has visible phenotype, enhanceable by Df(3L)mir-ban^Δ1

(Brennecke et al., 2003)

hid^GMR.PG has abnormal cell death phenotype, enhanceable by Diap1⁹

(Lisi et al., 2000)

hid^GMR.PG has abnormal cell death phenotype, enhanceable by Diap1^SL

(Lisi et al., 2000)

hid^GMR.PG has abnormal cell death phenotype, enhanceable by Df(3L)brm11

(Lisi et al., 2000)

hid^GMR.PG has abnormal cell death phenotype, enhanceable by Diap1^109.07

(Lisi et al., 2000)

hid^GMR.PG has abnormal cell death phenotype, enhanceable by Diap1⁴

(Lisi et al., 2000)

hid^GMR.PG has abnormal cell death phenotype, enhanceable by Diap1⁵

(Lisi et al., 2000)

hid^GMR.PG has abnormal cell death phenotype, enhanceable by Diap1⁷

(Lisi et al., 2000)

NOT Enhanced by

Statement

Reference

hid^GMR.PG has visible phenotype, non-enhanceable by Fak^UAS.Tag:HA/Scer\GAL4^GMR.PU

(Macagno et al., 2014)

hid^GMR.PG has visible phenotype, non-enhanceable by Tpr2^EB7-1A/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has visible phenotype, non-enhanceable by CG11700^EP1384/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has visible phenotype, non-enhanceable by Mad^unspecified

(Bach et al., 2003)

hid^GMR.PG has visible phenotype, non-enhanceable by Stat92E^unspecified

(Bach et al., 2003)

Suppressed by

Statement

Reference

hid^GMR.PG has visible | adult stage phenotype, suppressible | partially by spoon^KG02745

(Das et al., 2023)

hid^GMR.PG has decreased size | adult stage phenotype, suppressible | partially by spoon^KG02745

(Das et al., 2023)

hid^GMR.PG has increased cell death | larval stage phenotype, suppressible by Dronc^HMS00758/Scer\GAL4^mirr-DE

(Farrell et al., 2022)

hid^GMR.PG has decreased size | adult stage phenotype, suppressible | partially by Dronc^HMS00758/Scer\GAL4^mirr-DE

(Farrell et al., 2022)

hid^GMR.PG has visible | adult stage phenotype, suppressible by Scer\GAL4^ptc-559.1/Mnr^EP555

(Nagel et al., 2021)

hid^GMR.PG has decreased size | adult stage phenotype, suppressible by Scer\GAL4^ptc-559.1/Mnr^EP555

(Nagel et al., 2021)

hid^GMR.PG has abnormal size | adult stage phenotype, suppressible by Ae2^KK100095/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has visible | adult stage phenotype, suppressible by Ae2^KK100095/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has abnormal size | adult stage phenotype, suppressible by BacA\p35^UAS.cUa/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has visible | adult stage phenotype, suppressible by BacA\p35^UAS.cUa/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has visible | adult stage phenotype, suppressible by Dronc^I29

(Neukomm et al., 2017)

hid^GMR.PG has visible | adult stage phenotype, suppressible by Duba^GD11813/Scer\GAL4^GMR.PU

(Koerver et al., 2016)

hid^GMR.PG has visible | adult stage phenotype, suppressible by Duba^KK108478/Scer\GAL4^GMR.PU

(Koerver et al., 2016)

hid^GMR.PG has visible | adult stage phenotype, suppressible by Duba¹⁰⁷/Duba¹⁰⁷

(Koerver et al., 2016)

hid^GMR.PG has visible phenotype, suppressible by Drice^Δ1/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has visible phenotype, suppressible by Drice^L1/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has visible phenotype, suppressible by Drice^L2/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has visible phenotype, suppressible by Drice^C1/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has visible phenotype, suppressible by Drice^C2/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has visible phenotype, suppressible by Drice^S1/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has visible phenotype, suppressible by Drice^S2/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has visible phenotype, suppressible by Drice[+]/Drice^L1

(Wu et al., 2016)

hid^GMR.PG has visible phenotype, suppressible by Scer\GAL4^GMR.PF/Corp^EY03495

(Chakraborty et al., 2015)

hid^GMR.PG has increased cell death phenotype, suppressible by Scer\GAL4^GMR.PF/Corp^EY03495

(Chakraborty et al., 2015)

hid^GMR.PG has visible phenotype, suppressible by p53^5A-1-4

(Chakraborty et al., 2015)

Scer\GAL4^GMR.PF, hid^GMR.PG has visible phenotype, suppressible by CG3251^GD10916, Scer\GAL4^GMR.PF

(Louis et al., 2015)

Scer\GAL4^GMR.PF, hid^GMR.PG has increased cell death phenotype, suppressible by CG3251^GD10916, Scer\GAL4^GMR.PF

(Louis et al., 2015)

Scer\GAL4^GMR.PF, hid^GMR.PG has visible phenotype, suppressible by CG3251^KK106465, Scer\GAL4^GMR.PF

(Louis et al., 2015)

Scer\GAL4^GMR.PF, hid^GMR.PG has increased cell death phenotype, suppressible by CG3251^KK106465, Scer\GAL4^GMR.PF

(Louis et al., 2015)

hid^GMR.PG has visible phenotype, suppressible by Ret^GMR.PR

(Macagno et al., 2014)

hid^GMR.PG has increased cell death phenotype, suppressible by cos^H29

(Christiansen et al., 2013)

hid^GMR.PG has increased cell death phenotype, suppressible by Cdk7^S164A.T170A

(Morishita et al., 2013)

hid^GMR.PG has increased cell death | adult stage phenotype, suppressible by NetA^Δ

(Newquist et al., 2013)

Scer\GAL4^GMR.PU, hid^GMR.PG, yki^KK109756 has lethal | pharate adult stage phenotype, suppressible by Ack^UAS.cSb, Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has visible phenotype, suppressible by Ack^UAS.cSb/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has increased cell death phenotype, suppressible by Ack^UAS.cSb/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has visible phenotype, suppressible by yki^UAS.cHa/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has increased cell death phenotype, suppressible by Ras85D^R68Q

(Gafuik and Steller, 2011)

hid^GMR.PG has increased cell death phenotype, suppressible by Den1^VDRC.cUa/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

hid^GMR.PG has increased cell death phenotype, suppressible by CSN5^NIG.14884R/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

hid^GMR.PG has increased cell death phenotype, suppressible by CG1503^VDRC.cUa/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

hid^GMR.PG has increased cell death phenotype, suppressible by Den1^EX9

(Broemer et al., 2010)

hid^GMR.PG has increased cell death phenotype, suppressible by rpr^GD4698/Scer\GAL4^GMR.PF

(Sandu et al., 2010)

hid^GMR.PG has visible phenotype, suppressible by morgue¹²⁶/morgue[+]

(Schreader et al., 2010)

hid^GMR.PG has increased cell death phenotype, suppressible by morgue¹²⁶/morgue[+]

(Schreader et al., 2010)

hid^GMR.PG has visible phenotype, suppressible by morgue[+]/morgue⁴⁵⁷

(Schreader et al., 2010)

hid^GMR.PG has increased cell death phenotype, suppressible by morgue[+]/morgue⁴⁵⁷

(Schreader et al., 2010)

Scer\GAL4^GMR.PF, hid^GMR.PG, spen^RNAi.UAS has visible | adult stage phenotype, suppressible by nito^RNAi.UAS.cCa/Scer\GAL4^GMR.PF

(Chang et al., 2008)

Scer\GAL4^GMR.PF, hid^GMR.PG, spen^RNAi.UAS has abnormal size | adult stage phenotype, suppressible by nito^RNAi.UAS.cCa/Scer\GAL4^GMR.PF

(Chang et al., 2008)

Scer\GAL4^GMR.PF, hid^GMR.PG, nito^RNAi.UAS.cCa has visible | adult stage phenotype, suppressible | partially by spen^RNAi.UAS/Scer\GAL4^GMR.PF

(Chang et al., 2008)

Scer\GAL4^GMR.PF, hid^GMR.PG, nito^RNAi.UAS.cCa has abnormal size | adult stage phenotype, suppressible | partially by spen^RNAi.UAS/Scer\GAL4^GMR.PF

(Chang et al., 2008)

hid^GMR.PG has visible | adult stage phenotype, suppressible by nito^RNAi.UAS.cCa/Scer\GAL4^GMR.PF

(Chang et al., 2008)

hid^GMR.PG has abnormal size | adult stage phenotype, suppressible by nito^RNAi.UAS.cCa/Scer\GAL4^GMR.PF

(Chang et al., 2008)

hid^GMR.PG has visible phenotype, suppressible by Uba1^D6/Uba1^D6

(Lee et al., 2008)

hid^GMR.PG has visible phenotype, suppressible by Uba1^H33/Uba1^H33

(Lee et al., 2008)

hid^GMR.PG has visible phenotype, suppressible by Uba1^H42/Uba1^H42

(Lee et al., 2008)

hid^GMR.PG has increased cell death phenotype, suppressible by Uba1^D6/Uba1^D6

(Lee et al., 2008)

hid^GMR.PG has visible phenotype, suppressible by wech^JM265/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has visible phenotype, suppressible by Scer\GAL4^GMR.PU/Imp^EP1433

(Bilen and Bonini, 2007)

hid^GMR.PG has visible phenotype, suppressible by Scer\GAL4^GMR.PF/JMJD6^UAS.cKa

(Krieser et al., 2007)

hid^GMR.PG has visible phenotype, suppressible by Uba1^B2/Uba1^B2

(Pfleger et al., 2007)

hid^GMR.PG has increased cell death | larval stage phenotype, suppressible by Dark^G8

(Srivastava et al., 2007)

hid^GMR.PG has increased cell death phenotype, suppressible by Vps25^K2

(Herz et al., 2006)

hid^GMR.PG has increased cell death phenotype, suppressible by Vps25^N55

(Herz et al., 2006)

hid^GMR.PG has increased cell death phenotype, suppressible by Scer\GAL4^Tub.PU/upd1^UAS.cZa

(Herz et al., 2006)

hid^GMR.PG has visible phenotype, suppressible by Dronc^ΔA8/Dronc^ΔA8

(Kondo et al., 2006)

hid^GMR.PG has visible phenotype, suppressible by Drice^Δ2C8/Drice^Δ2C8

(Kondo et al., 2006)

hid^GMR.PG has increased cell death | third instar larval stage phenotype, suppressible by Dronc^ΔA8/Dronc^ΔA8

(Kondo et al., 2006)

hid^GMR.PG has increased cell death | third instar larval stage phenotype, suppressible by Drice^Δ2C8/Drice^Δ2C8

(Kondo et al., 2006)

Drice^RNAi.UAS.cLb, Scer\GAL4^GMR.PF, hid^GMR.PG has visible phenotype, suppressible | partially by Dcp-1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has visible phenotype, suppressible by Scer\GAL4^GMR.PF/Dronc^RNAi.UAS.cLa

(Leulier et al., 2006)

hid^GMR.PG has visible phenotype, suppressible by Dark^RNAi.UAS.cLa/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has visible phenotype, suppressible by Drice^RNAi.UAS.cLb/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has visible phenotype, suppressible by Scer\GAL4^GMR.PF/Strica^RNAi.UAS.cLa

(Leulier et al., 2006)

hid^GMR.PG has visible phenotype, suppressible by Decay^RNAi.UAS.cLa/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has visible phenotype, suppressible by Decay^RNAi.UAS.cLa/Scer\GAL4^GMR.PF/Dronc^RNAi.UAS.cLa

(Leulier et al., 2006)

hid^GMR.PG has visible phenotype, suppressible by Scer\GAL4^GMR.PF/Dronc^RNAi.UAS.cLa/Strica^RNAi.UAS.cLa

(Leulier et al., 2006)

hid^GMR.PG has visible phenotype, suppressible by Df(3R)Drice/Drice¹⁷

(Xu et al., 2006)

hid^GMR.PG has increased cell death phenotype, suppressible by mats^e235

(Lai et al., 2005)

hid^GMR.PG has visible phenotype, suppressible by Hr4^EP1232/Scer\GAL4^GMR.PF

(Müller et al., 2005)

hid^GMR.PG has visible phenotype, suppressible by mir-278^EP2316/Scer\GAL4^GMR.PF

(Müller et al., 2005)

hid^GMR.PG has visible phenotype, suppressible by Scer\GAL4^GMR.PF/Imp^EP1433

(Müller et al., 2005)

hid^GMR.PG has visible | somatic clone phenotype, suppressible by Dronc²/Dronc²

(Xu et al., 2005)

hid^GMR.PG has visible | somatic clone phenotype, suppressible by Dronc^I29/Dronc^I29

(Xu et al., 2005)

hid^GMR.PG has visible | somatic clone phenotype, suppressible by Dronc^L32/Dronc^L32

(Xu et al., 2005)

hid^GMR.PG has visible | somatic clone phenotype, suppressible by Dronc^I24/Dronc^I24

(Xu et al., 2005)

hid^GMR.PG has visible phenotype, suppressible by pnut[+]/pnut^XP

(Gottfried et al., 2004)

hid^GMR.PG has visible phenotype, suppressible by pnut[+]/pnut¹

(Gottfried et al., 2004)

hid^GMR.PG has visible phenotype, suppressible by klu[+]/klu^unspecified

(Rusconi et al., 2004)

hid^GMR.PG has visible phenotype, suppressible by gl^unspecified

(Bach et al., 2003)

hid^GMR.PG has visible phenotype, suppressible by mir-ban^EP3622/Scer\GAL4^GMR.PF

(Brennecke et al., 2003)

hid^GMR.PG has visible phenotype, suppressible by Df(2R)017/+

(Ditzel et al., 2003)

hid^GMR.PG has visible phenotype, suppressible by Df(2R)PC66/+

(Ditzel et al., 2003)

hid^GMR.PG has increased cell death | somatic clone phenotype, suppressible by hpo^BF33

(Jia et al., 2003)

hid^GMR.PG has increased cell death phenotype, suppressible by Scer\GAL4^Act5C.PP/hpo^RNAi.UAS.cPa

(Pantalacci et al., 2003)

hid^GMR.PG has visible phenotype, suppressible by morgue[+]/morgue^EP1184

(Hays et al., 2002)

hid^GMR.PG has increased cell death phenotype, suppressible by morgue[+]/morgue^EP1184

(Hays et al., 2002)

hid^GMR.PG has visible phenotype, suppressible by nmo^unspecified/nmo[+]

(Mirkovic et al., 2002)

Diap1⁵/th[+], hid^GMR.PG has increased cell death phenotype, suppressible by Dark^CD4

(Rodriguez et al., 2002)

hid^GMR.PG has visible phenotype, suppressible by eff⁵⁹⁸/eff[+]

(Ryoo et al., 2002)

hid^GMR.PG has visible phenotype, suppressible by eff[+]/eff^D73

(Ryoo et al., 2002)

hid^GMR.PG has increased cell death phenotype, suppressible by sav³

(Tapon et al., 2002)

hid^GMR.PG has visible phenotype, suppressible by Diap1^33-1s

(Wilson et al., 2002)

hid^GMR.PG has visible phenotype, suppressible by Diap1^21-4s

(Wilson et al., 2002)

hid^GMR.PG has visible phenotype, suppressible by Df(2L)morgue¹⁹/+

(Wing et al., 2002)

hid^GMR.PG has visible phenotype, suppressible by Damm^{C156G.GMR.Tag:FLAG}

(Harvey et al., 2001)

hid^GMR.PG has abnormal cell death phenotype, suppressible by Diap1^6B

(Lisi et al., 2000)

hid^GMR.PG has abnormal cell death phenotype, suppressible by Diap1^81.03

(Lisi et al., 2000)

hid^GMR.PG has abnormal cell death phenotype, suppressible by Diap1^UAS.cLa/Scer\GAL4^GMR.PF

(Lisi et al., 2000)

hid^GMR.PG has abnormal cell death phenotype, suppressible by Diap1^V85M.UAS/Scer\GAL4^GMR.PF

(Lisi et al., 2000)

hid^GMR.PG has visible phenotype, suppressible by Df(3L)AC1

(Quinn et al., 2000)

hid^GMR.PG has abnormal cell death phenotype, suppressible by cln^SF3-2

(Taguchi et al., 2000)

hid^GMR.PG has abnormal cell death phenotype, suppressible by cln^SF3-3

(Taguchi et al., 2000)

hid^GMR.PG has visible phenotype, suppressible by Dark^CD4

(Rodriguez et al., 1999)

hid^GMR.PG has abnormal cell death phenotype, suppressible by Diap2^GMR.PH

(Hay et al., 1995)

hid^GMR.PG has abnormal cell death phenotype, suppressible by Diap1^GMR.PH

(Hay et al., 1995)

NOT suppressed by

Statement

Reference

hid^GMR.PG has decreased size | adult stage phenotype, non-suppressible by Scer\GAL4^mirr-DE/LIMK1^HMS04455

(Farrell et al., 2022)

hid^GMR.PG has increased cell death | larval stage phenotype, non-suppressible by Scer\GAL4^mirr-DE/LIMK1^HMS04455

(Farrell et al., 2022)

hid^GMR.PG has decreased size | adult stage phenotype, non-suppressible by Scer\GAL4^mirr-DE/tsr^UAS.cNa

(Farrell et al., 2022)

hid^GMR.PG has increased cell death | larval stage phenotype, non-suppressible by Scer\GAL4^mirr-DE/tsr^UAS.cNa

(Farrell et al., 2022)

hid^GMR.PG has abnormal size | adult stage phenotype, non-suppressible by CG13384^HMS02268/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has visible | adult stage phenotype, non-suppressible by CG13384^HMS02268/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has abnormal size | adult stage phenotype, non-suppressible by CG10413^KK102660/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has visible | adult stage phenotype, non-suppressible by CG10413^KK102660/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has abnormal size | adult stage phenotype, non-suppressible by hrm^GD1807/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has visible | adult stage phenotype, non-suppressible by hrm^GD1807/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has abnormal size | adult stage phenotype, non-suppressible by CG5805^GD12806/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has visible | adult stage phenotype, non-suppressible by CG5805^GD12806/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has visible | adult stage phenotype, non-suppressible by axed²⁰⁹⁴

(Neukomm et al., 2017)

hid^GMR.PG has visible phenotype, non-suppressible by Drice[+]/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has visible phenotype, non-suppressible by Fak^UAS.Tag:HA/Scer\GAL4^GMR.PU

(Macagno et al., 2014)

hid^GMR.PG has increased cell death | third instar larval stage phenotype, non-suppressible by Clbn^1Q/Clbn^1Q

(Wang et al., 2013)

hid^GMR.PG has visible phenotype, non-suppressible by Sarm⁸⁹⁶

(Osterloh et al., 2012)

hid^GMR.PG has visible phenotype, non-suppressible by Ack^K156A.UAS/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has visible phenotype, non-suppressible by drk^KK109233/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has visible phenotype, non-suppressible by yki[+]/yki^B5

(Schoenherr et al., 2012)

hid^GMR.PG has visible phenotype, non-suppressible by DJ-1α^UAS.cUa/Scer\GAL4^GMR.PU

(Hao et al., 2010)

hid^GMR.PG has visible phenotype, non-suppressible by scny^D.GMR

(Ribaya et al., 2009)

hid^GMR.PG has visible | adult stage phenotype, non-suppressible by spen^RNAi.UAS/Scer\GAL4^GMR.PF

(Chang et al., 2008)

hid^GMR.PG has abnormal size | adult stage phenotype, non-suppressible by spen^RNAi.UAS/Scer\GAL4^GMR.PF

(Chang et al., 2008)

hid^GMR.PG has visible phenotype, non-suppressible by Tpr2^EB7-1A/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has visible phenotype, non-suppressible by CG11700^EP1384/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has increased cell death phenotype, non-suppressible by FHV\B2^UAS.HM/Scer\GAL4^GMR.PF

(Chou et al., 2007)

hid^GMR.PG has increased cell death phenotype, non-suppressible by NDV\B2^UAS.HM/Scer\GAL4^GMR.PF

(Chou et al., 2007)

hid^GMR.PG has increased cell death phenotype, non-suppressible by Scer\GAL4^GMR.PF/VV\E3L^UAS.HM

(Chou et al., 2007)

hid^GMR.PG has increased cell death phenotype, non-suppressible by TBSV\P19^UAS.HM/Scer\GAL4^GMR.PF

(Chou et al., 2007)

hid^GMR.PG has increased cell death phenotype, non-suppressible by Scer\GAL4^GMR.PF/Ivir\NS1^UAS.HM

(Chou et al., 2007)

hid^GMR.PG has visible phenotype, non-suppressible by Dredd^B118

(Kondo et al., 2006)

hid^GMR.PG has visible phenotype, non-suppressible by Decay^ΔK2/Decay^ΔK2

(Kondo et al., 2006)

hid^GMR.PG has visible phenotype, non-suppressible by Dcp-1^Prev1/Dcp-1^Prev1

(Kondo et al., 2006)

hid^GMR.PG has visible phenotype, non-suppressible by Fadd^RNAi.UAS.cLa/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has visible phenotype, non-suppressible by Scer\GAL4^GMR.PF/Damm^RNAi.UAS.cLa

(Leulier et al., 2006)

hid^GMR.PG has visible phenotype, non-suppressible by Dredd^RNAi.UAS.cLa/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has visible phenotype, non-suppressible by Dcp-1^RNAi.UAS.cLa/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has abnormal size | adult stage phenotype, non-suppressible by mir-278^mirvana-1/Scer\GAL4^GMR.PF

(Nairz et al., 2006)

hid^GMR.PG has abnormal size | adult stage phenotype, non-suppressible by mir-278^mirvana-1/Df(2R)Exel7137

(Nairz et al., 2006)

hid^GMR.PG has visible | somatic clone phenotype, non-suppressible by Dronc^I24/Nc[+]

(Xu et al., 2005)

hid^GMR.PG has visible phenotype, non-suppressible by Dark^unspecified/Ark[+]

(Gottfried et al., 2004)

hid^GMR.PG has visible phenotype, non-suppressible by Mad^unspecified

(Bach et al., 2003)

hid^GMR.PG has visible phenotype, non-suppressible by Stat92E^unspecified

(Bach et al., 2003)

hid^GMR.PG has visible phenotype, non-suppressible by spen^DN.UAS/Scer\GAL4^GMR.PF

(Lin et al., 2003)

hid^GMR.PG has visible phenotype, non-suppressible by TER94[+]/TER94^26-8

(Higashiyama et al., 2002)

hid^GMR.PG has visible phenotype, non-suppressible by Dark^k11502

(Kanuka et al., 1999)

Enhancer of

Statement

Reference

hid^GMR.PG is an enhancer of visible phenotype of Dcp-1^fl.GMR

(Song et al., 2000)

Suppressor of

Statement

Reference

hid^GMR.PG is a suppressor of photoperiod response variant phenotype of cry^b

(Klarsfeld et al., 2004)

NOT Suppressor of

Statement

Reference

hid^GMR.PG is a non-suppressor of photoperiod response variant phenotype of Pdf⁰¹

(Klarsfeld et al., 2004)

hid^GMR.PG is a non-suppressor of abnormal locomotor rhythm phenotype of Pdf⁰¹

(Klarsfeld et al., 2004)

hid^GMR.PG is a non-suppressor of abnormal locomotor rhythm phenotype of cry^b

(Klarsfeld et al., 2004)

Other

Statement

Reference

Scer\GAL4^GMR.PU, hid^GMR.PG, yki^UAS.cHa has abnormal eye color phenotype

(Schoenherr et al., 2012)

Scer\GAL4^GMR.PU, hid^GMR.PG, yki^KK109756 has lethal | pharate adult stage phenotype

(Schoenherr et al., 2012)

Scer\GAL4^P2.4.Pdf, cry^RNAi.UAS.cPa, hid^GMR.PG has abnormal locomotor rhythm phenotype

(Picot et al., 2007)

hid^GMR.PG, scrib¹ has lethal phenotype

(Brumby and Richardson, 2003)

hid^GMR.PG, scrib¹ has hyperplasia | somatic clone | larval stage phenotype

(Brumby and Richardson, 2003)

Diap1⁵/th[+], hid^GMR.PG has increased cell death phenotype

(Rodriguez et al., 2002)

Diap1⁵, hid^GMR.PG has increased cell death phenotype

(Rodriguez et al., 2002)

Phenotype Manifest In

Enhanced by

Statement

Reference

Ret^GMR.PR, hid^GMR.PG has eye phenotype, enhanceable by Fak^UAS.Tag:HA/Scer\GAL4^GMR.PU

(Macagno et al., 2014)

hid^GMR.PG has eye phenotype, enhanceable by DUBAI^GD14040/Scer\GAL4^GMR.PFa

(Yang et al., 2014)

hid^GMR.PG has eye phenotype, enhanceable by CG8830[+]/DUBAI^KG07439

(Yang et al., 2014)

hid^GMR.PG has eye phenotype, enhanceable by smo^D16

(Christiansen et al., 2013)

hid^GMR.PG has eye phenotype, enhanceable by Ack⁸⁶/Ack⁸⁶

(Schoenherr et al., 2012)

hid^GMR.PG has eye phenotype, enhanceable by Ack^GD8506/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has eye phenotype, enhanceable by Rab11^mo

(Tiwari and Roy, 2009)

hid^GMR.PG has eye phenotype, enhanceable by Acox1^B227.2/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has eye phenotype, enhanceable by emb^E2-1A/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has eye phenotype, enhanceable by PSR[+]/JMJD6^FM1

(Krieser et al., 2007)

hid^GMR.PG has eye phenotype, enhanceable by JMJD6^FM1/JMJD6^FM1

(Krieser et al., 2007)

hid^GMR.PG has eye phenotype, enhanceable by D^unspecified

(Bach et al., 2003)

hid^GMR.PG has eye phenotype, enhanceable by Df(3L)mir-ban^Δ1

(Brennecke et al., 2003)

hid^GMR.PG has eye disc phenotype, enhanceable by hpo^BF33

(Jia et al., 2003)

hid^GMR.PG has phenotype, enhanceable by Diap1^11-3e

(Goyal et al., 2000)

hid^GMR.PG has phenotype, enhanceable by Diap1⁴

(Goyal et al., 2000)

hid^GMR.PG has phenotype, enhanceable by Diap1⁵

(Goyal et al., 2000)

hid^GMR.PG has eye phenotype, enhanceable by Diap1^109.07

(Lisi et al., 2000)

hid^GMR.PG has eye phenotype, enhanceable by Diap1⁴

(Lisi et al., 2000, Hay et al., 1995)

hid^GMR.PG has eye phenotype, enhanceable by Diap1⁵

(Lisi et al., 2000, Hay et al., 1995)

hid^GMR.PG has eye phenotype, enhanceable by Diap1⁷

(Lisi et al., 2000, Hay et al., 1995)

hid^GMR.PG has eye phenotype, enhanceable by Diap1⁹

(Lisi et al., 2000)

hid^GMR.PG has eye phenotype, enhanceable by Diap1^SL

(Lisi et al., 2000)

hid^GMR.PG has eye phenotype, enhanceable by Egfr^f2

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, enhanceable by Egfr^f2

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, enhanceable by Ras85D^ΔC40B

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, enhanceable by Ras85D^ΔC40B

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, enhanceable by Ras85D^N17.sev

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, enhanceable by Ras85D^N17.sev

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, enhanceable by Raf¹¹

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, enhanceable by Raf¹¹

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, enhanceable by rl^10a

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, enhanceable by rl^10a

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, enhanceable by Dsor1^LF133

(Kurada and White, 1998)

hid^GMR.PG has eye phenotype, enhanceable by Egfr^f1

(Kurada and White, 1998)

hid^GMR.PG has eye phenotype, enhanceable by Ras85D^N17.hs.2sev

(Kurada and White, 1998)

hid^GMR.PG has eye phenotype, enhanceable by Ras85D^e2F

(Kurada and White, 1998)

hid^GMR.PG has eye phenotype, enhanceable by Raf⁷

(Kurada and White, 1998)

hid^GMR.PG has eye phenotype, enhanceable by pnt^07825Δ78

(Kurada and White, 1998)

hid^GMR.PG has eye phenotype, enhanceable by rl^S-694

(Kurada and White, 1998)

hid^GMR.PG has eye phenotype, enhanceable by Diap1⁶

(Hay et al., 1995)

hid^GMR.PG has eye phenotype, enhanceable by Diap1⁸

(Hay et al., 1995)

NOT Enhanced by

Statement

Reference

hid^GMR.PG has eye phenotype, non-enhanceable by Fak^UAS.Tag:HA/Scer\GAL4^GMR.PU

(Macagno et al., 2014)

hid^GMR.PG has eye phenotype, non-enhanceable by Scer\GAL4^αTub84B.PZ/ci^{Ce-2.UAS.Tag:HA}

(Christiansen et al., 2013)

hid^GMR.PG has eye phenotype, non-enhanceable by Debcl⁵⁹

(Galindo et al., 2009)

hid^GMR.PG has eye phenotype, non-enhanceable by lncRNA:Hsrω^EP3037/Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

hid^GMR.PG has eye phenotype, non-enhanceable by Tpr2^EB7-1A/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has eye phenotype, non-enhanceable by CG11700^EP1384/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has ommatidium phenotype, non-enhanceable by mir-278^mirvana-1/mir-278^mirvana-1

(Nairz et al., 2006)

hid^GMR.PG has interommatidial bristle phenotype, non-enhanceable by mir-278^mirvana-1/mir-278^mirvana-1

(Nairz et al., 2006)

hid^GMR.PG has ommatidium phenotype, non-enhanceable by mir-278^mirvana-1/Df(2R)Exel7137

(Nairz et al., 2006)

hid^GMR.PG has interommatidial bristle phenotype, non-enhanceable by mir-278^mirvana-1/Df(2R)Exel7137

(Nairz et al., 2006)

hid^GMR.PG has eye phenotype, non-enhanceable by Mad^unspecified

(Bach et al., 2003)

hid^GMR.PG has eye phenotype, non-enhanceable by Stat92E^unspecified

(Bach et al., 2003)

hid^GMR.PG has phenotype, non-enhanceable by Bruce^unspecified/Bruce[+]

(Ryoo et al., 2002)

hid^GMR.PG has phenotype, non-enhanceable by Df(3R)faf-BP/+

(Ryoo et al., 2002)

hid^GMR.PG has phenotype, non-enhanceable by Pros26[+]/Prosβ6¹

(Ryoo et al., 2002)

hid^GMR.PG has phenotype, non-enhanceable by Ubc2^k13206

(Ryoo et al., 2002)

hid^GMR.PG has phenotype, non-enhanceable by lwr^unspecified

(Ryoo et al., 2002)

hid^GMR.PG has phenotype, non-enhanceable by Drice^fl.GMR

(Song et al., 2000)

hid^GMR.PG has phenotype, non-enhanceable by EM3-1^EM3-1

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-enhanceable by S^EF2-1

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-enhanceable by S^EM2-4

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-enhanceable by SM2-1^SM2-1

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-enhanceable by SM3-2^SM3-2

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-enhanceable by SM3-3^SM3-3

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-enhanceable by SM3-6^SM3-6

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-enhanceable by SM3-8^SM3-8

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-enhanceable by bul^SF3-1

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-enhanceable by sty^SM3-5

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-enhanceable by sty^SM3-9

(Taguchi et al., 2000)

Suppressed by

Statement

Reference

hid^GMR.PG has ommatidium | decreased number phenotype, suppressible | partially by spoon^KG02745

(Das et al., 2023)

hid^GMR.PG has eye phenotype, suppressible | partially by spoon^KG02745

(Das et al., 2023)

hid^GMR.PG has eye disc | larval stage phenotype, suppressible by Dronc^HMS00758/Scer\GAL4^mirr-DE

(Farrell et al., 2022)

hid^GMR.PG has eye | adult stage phenotype, suppressible | partially by Dronc^HMS00758/Scer\GAL4^mirr-DE

(Farrell et al., 2022)

hid^GMR.PG has eye phenotype, suppressible by Mnr^EP555/Scer\GAL4^GMR.PU

(Nagel et al., 2021)

hid^GMR.PG has eye phenotype, suppressible by CG10413^KK102660/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has eye phenotype, suppressible by BacA\p35^UAS.cUa/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has eye phenotype, suppressible by Dronc^I29

(Neukomm et al., 2017)

hid^GMR.PG has eye | adult stage phenotype, suppressible by Duba^GD11813/Scer\GAL4^GMR.PU

(Koerver et al., 2016)

hid^GMR.PG has eye | adult stage phenotype, suppressible by Duba^KK108478/Scer\GAL4^GMR.PU

(Koerver et al., 2016)

hid^GMR.PG has eye | adult stage phenotype, suppressible by Duba¹⁰⁷/Duba¹⁰⁷

(Koerver et al., 2016)

hid^GMR.PG has eye phenotype, suppressible by Drice^Δ1/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has eye phenotype, suppressible by Drice^L1/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has eye phenotype, suppressible by Drice^L2/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has eye phenotype, suppressible by Drice^C1/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has eye phenotype, suppressible by Drice^C2/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has eye phenotype, suppressible by Drice^S1/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has eye phenotype, suppressible by Drice^S2/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has eye phenotype, suppressible by Drice[+]/Drice^L1

(Wu et al., 2016)

hid^GMR.PG has eye phenotype, suppressible by Scer\GAL4^GMR.PF/Corp^EY03495

(Chakraborty et al., 2015)

hid^GMR.PG has eye phenotype, suppressible by p53^5A-1-4

(Chakraborty et al., 2015)

Scer\GAL4^GMR.PF, hid^GMR.PG has eye phenotype, suppressible by CG3251^GD10916, Scer\GAL4^GMR.PF

(Louis et al., 2015)

Scer\GAL4^GMR.PF, hid^GMR.PG has eye phenotype, suppressible by CG3251^KK106465, Scer\GAL4^GMR.PF

(Louis et al., 2015)

hid^GMR.PG has eye phenotype, suppressible by Ret^GMR.PR

(Macagno et al., 2014)

hid^GMR.PG has eye phenotype, suppressible by cos^H29

(Christiansen et al., 2013)

hid^GMR.PG has eye phenotype, suppressible by cos^L51

(Christiansen et al., 2013)

hid^GMR.PG has eye phenotype, suppressible by cos^P50

(Christiansen et al., 2013)

hid^GMR.PG has eye phenotype, suppressible by ptc^C

(Christiansen et al., 2013)

hid^GMR.PG has eye phenotype, suppressible by ptc^L49

(Christiansen et al., 2013)

hid^GMR.PG has eye phenotype, suppressible by Pka-C1^K2

(Christiansen et al., 2013)

hid^GMR.PG has eye phenotype, suppressible by Pka-C1^B3

(Christiansen et al., 2013)

hid^GMR.PG has eye phenotype, suppressible by Uba1^H42

(Christiansen et al., 2013)

hid^GMR.PG has eye phenotype, suppressible by Cdk7^S164A.T170A

(Morishita et al., 2013)

hid^GMR.PG has eye phenotype, suppressible by NetA^Δ

(Newquist et al., 2013)

hid^GMR.PG has eye phenotype, suppressible by NetB^Δ

(Newquist et al., 2013)

hid^GMR.PG has eye phenotype, suppressible by Bruce^BIR.UAS/Scer\GAL4^GMR.PF

(Domingues and Ryoo, 2012)

hid^GMR.PG has eye phenotype, suppressible by Bruce^UAS.Tag:MYC/Scer\GAL4^GMR.PF

(Domingues and Ryoo, 2012)

hid^GMR.PG has eye phenotype, suppressible by Ack^UAS.cSb/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has eye disc phenotype, suppressible by Ack^UAS.cSb/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has eye phenotype, suppressible by yki^UAS.cHa/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has eye phenotype, suppressible by Den1^VDRC.cUa/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

hid^GMR.PG has eye phenotype, suppressible by CSN5^NIG.14884R/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

hid^GMR.PG has eye phenotype, suppressible by CG1503^VDRC.cUa/Scer\GAL4^GMR.PF

(Broemer et al., 2010)

hid^GMR.PG has eye phenotype, suppressible by Den1^EX9

(Broemer et al., 2010)

hid^GMR.PG has eye phenotype, suppressible by rpr^GD4698/Scer\GAL4^GMR.PF

(Sandu et al., 2010)

hid^GMR.PG has eye phenotype, suppressible by morgue¹²⁶/morgue[+]

(Schreader et al., 2010)

hid^GMR.PG has eye phenotype, suppressible by morgue[+]/morgue⁴⁵⁷

(Schreader et al., 2010)

hid^GMR.PG has eye phenotype, suppressible by Vps25^N55

(Herz et al., 2009, Herz et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Vps36^L5212

(Herz et al., 2009)

hid^GMR.PG has eye phenotype, suppressible by lncRNA:Hsrω^RNAi.Sym.UAS/Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Scer\GAL4^GMR.PF, hid^GMR.PG, spen^RNAi.UAS has eye phenotype, suppressible | partially by nito^RNAi.UAS.cCa/Scer\GAL4^GMR.PF

(Chang et al., 2008)

Scer\GAL4^GMR.PF, hid^GMR.PG, nito^RNAi.UAS.cCa has eye phenotype, suppressible | partially by spen^RNAi.UAS/Scer\GAL4^GMR.PF

(Chang et al., 2008)

Scer\GAL4^GMR.PF, hid^GMR.PG has eye phenotype, suppressible by nito^RNAi.UAS.cCa/Scer\GAL4^GMR.PF

(Chang et al., 2008)

hid^GMR.PG has eye phenotype, suppressible by Uba1^D6/Uba1^D6

(Lee et al., 2008)

hid^GMR.PG has eye disc phenotype, suppressible by Uba1^D6/Uba1^D6

(Lee et al., 2008)

hid^GMR.PG has eye phenotype, suppressible by Uba1^H33/Uba1^H33

(Lee et al., 2008)

hid^GMR.PG has eye phenotype, suppressible by Uba1^H42/Uba1^H42

(Lee et al., 2008)

hid^GMR.PG has eye | somatic clone phenotype, suppressible by Cbl^K26

(Wang et al., 2008)

hid^GMR.PG has eye | somatic clone phenotype, suppressible by Cbl⁸

(Wang et al., 2008)

hid^GMR.PG has eye | somatic clone phenotype, suppressible by Cbl⁴

(Wang et al., 2008)

hid^GMR.PG has eye | somatic clone phenotype, suppressible by Cbl^L31

(Wang et al., 2008)

hid^GMR.PG has eye | somatic clone phenotype, suppressible by Cbl⁷

(Wang et al., 2008)

hid^GMR.PG has eye phenotype, suppressible by wech^JM265/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has eye phenotype, suppressible by Scer\GAL4^GMR.PU/Imp^EP1433

(Bilen and Bonini, 2007)

hid^GMR.PG has eye phenotype, suppressible by Scer\GAL4^GMR.PF/JMJD6^UAS.cKa

(Krieser et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Uba1^B2/Uba1^B2

(Pfleger et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^A3b

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^A5

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^A24

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^B5

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^B15

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^C1

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^C4

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^D3

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^D4

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^E4

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^G8

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^G15

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^G29

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^H16

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^H28

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^H36

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^J15

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^L46

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^N28

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^N52

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^P13

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^P15

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^P46

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^P56

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^S7

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^S9

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^B2

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^I1

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^J7

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^N5

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^N10

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^A6

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Dark^M20

(Srivastava et al., 2007)

hid^GMR.PG has eye phenotype, suppressible by Vps25^K2

(Herz et al., 2006)

hid^GMR.PG has eye | somatic clone | cell non-autonomous phenotype, suppressible by Vps25^N55/Vps25^K2

(Herz et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Dronc^ΔA8/Dronc^ΔA8

(Kondo et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Drice^Δ2C8/Drice^Δ2C8

(Kondo et al., 2006)

hid^GMR.PG has eye disc phenotype, suppressible by Dronc^ΔA8/Dronc^ΔA8

(Kondo et al., 2006)

hid^GMR.PG has eye disc phenotype, suppressible by Drice^Δ2C8/Drice^Δ2C8

(Kondo et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Scer\GAL4^GMR.PF/Dronc^RNAi.UAS.cLa

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Dark^RNAi.UAS.cLa/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Drice^RNAi.UAS.cLb/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Scer\GAL4^GMR.PF/Strica^RNAi.UAS.cLa

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Decay^RNAi.UAS.cLa/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Decay^RNAi.UAS.cLa/Scer\GAL4^GMR.PF/Dronc^RNAi.UAS.cLa

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Scer\GAL4^GMR.PF/Dronc^RNAi.UAS.cLa/Strica^RNAi.UAS.cLa

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Drice^RNAi.UAS.cLb/Dcp-1^RNAi.UAS.cLa/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Drice^Δ1/Drice^Δ1

(Muro et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by Df(3R)Drice/Drice¹⁷

(Xu et al., 2006)

hid^GMR.PG has eye phenotype, suppressible by mats^e235

(Lai et al., 2005)

hid^GMR.PG has eye phenotype, suppressible by Hr4^EP1232/Scer\GAL4^GMR.PF

(Müller et al., 2005)

hid^GMR.PG has eye phenotype, suppressible by mir-278^EP2316/Scer\GAL4^GMR.PF

(Müller et al., 2005)

hid^GMR.PG has eye phenotype, suppressible by Scer\GAL4^GMR.PF/Imp^EP1433

(Müller et al., 2005)

hid^GMR.PG has eye phenotype, suppressible by lz^ts1

(Wildonger et al., 2005)

hid^GMR.PG has eye | somatic clone phenotype, suppressible by Dronc²/Dronc²

(Xu et al., 2005)

hid^GMR.PG has eye | somatic clone phenotype, suppressible by Dronc^I24/Dronc^I24

(Xu et al., 2005)

hid^GMR.PG has eye | somatic clone phenotype, suppressible by Dronc^I29/Dronc^I29

(Xu et al., 2005)

hid^GMR.PG has eye | somatic clone phenotype, suppressible by Dronc^L32/Dronc^L32

(Xu et al., 2005)

hid^GMR.PG has eye phenotype, suppressible by pnut[+]/pnut¹

(Gottfried et al., 2004)

hid^GMR.PG has eye phenotype, suppressible by pnut[+]/pnut^XP

(Gottfried et al., 2004)

hid^GMR.PG has ommatidium phenotype, suppressible by klu[+]/klu^unspecified

(Rusconi et al., 2004)

hid^GMR.PG has ommatidium phenotype, suppressible by Rcc1^XX138

(Shi and Skeath, 2004)

hid^GMR.PG has ommatidium phenotype, suppressible by Rcc1^FF32

(Shi and Skeath, 2004)

hid^GMR.PG has eye phenotype, suppressible by gl^unspecified

(Bach et al., 2003)

hid^GMR.PG has eye phenotype, suppressible by mir-ban^EP3622/Scer\GAL4^GMR.PF

(Brennecke et al., 2003)

hid^GMR.PG has eye phenotype, suppressible by Df(2R)017/+

(Ditzel et al., 2003)

hid^GMR.PG has eye phenotype, suppressible by Df(2R)PC66/+

(Ditzel et al., 2003)

hid^GMR.PG has eye phenotype, suppressible by Buffy^{ΔN.UAS.Tag:FLAG}/Scer\GAL4^GMR.PF

(Quinn et al., 2003)

hid^GMR.PG has eye phenotype, suppressible by Buffy^UAS.cQa/Scer\GAL4^GMR.PF

(Quinn et al., 2003)

hid^GMR.PG has eye phenotype, suppressible by morgue[+]/morgue^EP1184

(Hays et al., 2002)

hid^GMR.PG has ommatidium phenotype, suppressible by morgue[+]/morgue^EP1184

(Hays et al., 2002)

hid^GMR.PG has eye phenotype, suppressible by nmo^unspecified/nmo[+]

(Mirkovic et al., 2002)

hid^GMR.PG has eye phenotype, suppressible by eff⁵⁹⁸/eff[+]

(Ryoo et al., 2002)

hid^GMR.PG has eye phenotype, suppressible by eff[+]/eff^D73

(Ryoo et al., 2002)

hid^GMR.PG has eye phenotype, suppressible by Diap1^21-4s

(Wilson et al., 2002)

hid^GMR.PG has eye phenotype, suppressible by Diap1^33-1s

(Wilson et al., 2002)

hid^GMR.PG has eye phenotype, suppressible by Df(2L)morgue¹⁹/+

(Wing et al., 2002)

hid^GMR.PG has eye phenotype, suppressible by Damm^{C156G.GMR.Tag:FLAG}

(Harvey et al., 2001)

hid^GMR.PG has phenotype, suppressible by Diap1^21-2s

(Goyal et al., 2000)

hid^GMR.PG has phenotype, suppressible by Diap1^23-4s

(Goyal et al., 2000)

hid^GMR.PG has phenotype, suppressible by Diap1^23-8s

(Goyal et al., 2000)

hid^GMR.PG has phenotype, suppressible by Diap1^45-2s

(Goyal et al., 2000)

hid^GMR.PG has phenotype, suppressible by Diap1^6-3s

(Goyal et al., 2000)

hid^GMR.PG has eye phenotype, suppressible by Diap1^6B

(Lisi et al., 2000)

hid^GMR.PG has eye phenotype, suppressible by Diap1^81.03

(Lisi et al., 2000)

hid^GMR.PG has eye phenotype, suppressible by Diap1^UAS.cLa/Scer\GAL4^GMR.PF

(Lisi et al., 2000)

hid^GMR.PG has eye phenotype, suppressible by Diap1^V85M.UAS/Scer\GAL4^GMR.PF

(Lisi et al., 2000)

hid^GMR.PG has phenotype, suppressible by Df(3L)AC1

(Meier et al., 2000)

hid^GMR.PG has eye phenotype, suppressible by Df(3L)AC1

(Quinn et al., 2000)

hid^GMR.PG has phenotype, suppressible by E(rst)H42^H42

(Tanenbaum et al., 2000)

hid^GMR.PG has ommatidium phenotype, suppressible by Dark^CD4

(Rodriguez et al., 1999)

hid^GMR.PG has eye phenotype, suppressible by Dark^CD4

(Rodriguez et al., 1999)

hid^GMR.PG has eye phenotype, suppressible by Scer\GAL4^hs.2sev/Ras85D^V12.S35.UAS

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, suppressible by Scer\GAL4^hs.2sev/Ras85D^V12.S35.UAS

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, suppressible by Ras85D^V12.C40.UAS/Scer\GAL4^hs.2sev

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, suppressible by Ras85D^V12.C40.UAS/Scer\GAL4^hs.2sev

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, suppressible by Diap1^GMR.PH

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, suppressible by Diap1^GMR.PH

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, suppressible by RasGAP1^21-1s

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, suppressible by RasGAP1^21-1s

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, suppressible by sty^28-4s

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, suppressible by sty^28-4s

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, suppressible by aos^Δ7

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, suppressible by aos^Δ7

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, suppressible by Egfr^E1

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, suppressible by Egfr^E1

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, suppressible by Ras85D^V12.sev

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, suppressible by Raf::tor^hs.sev

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, suppressible by Raf::tor^hs.sev

(Bergmann et al., 1998)

hid^GMR.PG has ommatidium phenotype, suppressible by rl^Sem

(Bergmann et al., 1998)

hid^GMR.PG has eye phenotype, suppressible by Dsor1^Su1

(Kurada and White, 1998, Sawamoto et al., 1998)

hid^GMR.PG has eye phenotype, suppressible by Ras85D^V12.sev

(Bergmann et al., 1998, Kurada and White, 1998)

hid^GMR.PG has eye phenotype, suppressible by rl^Sem

(Bergmann et al., 1998, Kurada and White, 1998)

hid^GMR.PG has eye disc phenotype, suppressible by Dsor1^Su1

(Sawamoto et al., 1998)

hid^GMR.PG has eye phenotype, suppressible by rl^Su23

(Sawamoto et al., 1998)

hid^GMR.PG has eye disc phenotype, suppressible by rl^Su23

(Sawamoto et al., 1998)

NOT suppressed by

Statement

Reference

hid^GMR.PG has eye disc | larval stage phenotype, non-suppressible by Scer\GAL4^mirr-DE/LIMK1^HMS04455

(Farrell et al., 2022)

hid^GMR.PG has eye | adult stage phenotype, non-suppressible by Scer\GAL4^mirr-DE/LIMK1^HMS04455

(Farrell et al., 2022)

hid^GMR.PG has eye disc | larval stage phenotype, non-suppressible by Scer\GAL4^mirr-DE/tsr^UAS.cNa

(Farrell et al., 2022)

hid^GMR.PG has eye | adult stage phenotype, non-suppressible by Scer\GAL4^mirr-DE/tsr^UAS.cNa

(Farrell et al., 2022)

hid^GMR.PG has eye phenotype, non-suppressible by hrm^GD1807/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has eye phenotype, non-suppressible by CG5805^GD12806/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has eye phenotype, non-suppressible by CG13384^HMS02268/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has eye phenotype, non-suppressible by Ae2^KK100095/Scer\GAL4^GMR.PU

(Velentzas et al., 2018)

hid^GMR.PG has eye phenotype, non-suppressible by axed²⁰⁹⁴

(Neukomm et al., 2017)

hid^GMR.PG has eye phenotype, non-suppressible by Drice[+]/Drice¹⁷

(Wu et al., 2016)

hid^GMR.PG has eye phenotype, non-suppressible by Fak^UAS.Tag:HA/Scer\GAL4^GMR.PU

(Macagno et al., 2014)

hid^GMR.PG has eye phenotype, non-suppressible by Scer\GAL4^αTub84B.PZ/ci^{Ce-2.UAS.Tag:HA}

(Christiansen et al., 2013)

hid^GMR.PG has eye disc | third instar larval stage phenotype, non-suppressible by Clbn^1Q/Clbn^1Q

(Wang et al., 2013)

hid^GMR.PG has eye phenotype, non-suppressible by Sarm⁸⁹⁶

(Osterloh et al., 2012)

hid^GMR.PG has eye phenotype, non-suppressible by Ack^K156A.UAS/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has eye phenotype, non-suppressible by drk^KK109233/Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

hid^GMR.PG has eye phenotype, non-suppressible by yki[+]/yki^B5

(Schoenherr et al., 2012)

hid^GMR.PG has eye phenotype, non-suppressible by DJ-1α^UAS.cUa/Scer\GAL4^GMR.PU

(Hao et al., 2010)

hid^GMR.PG has eye phenotype, non-suppressible by Debcl⁵⁹

(Galindo et al., 2009)

hid^GMR.PG has eye phenotype, non-suppressible by lsn^5F3-8

(Herz et al., 2009)

hid^GMR.PG has eye phenotype, non-suppressible by scny^D.GMR

(Ribaya et al., 2009)

Scer\GAL4^GMR.PF, hid^GMR.PG has eye phenotype, non-suppressible by spen^RNAi.UAS/Scer\GAL4^GMR.PF

(Chang et al., 2008)

hid^GMR.PG has eye phenotype, non-suppressible by Tpr2^EB7-1A/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has eye phenotype, non-suppressible by CG11700^EP1384/Scer\GAL4^GMR.PU

(Bilen and Bonini, 2007)

hid^GMR.PG has eye phenotype, non-suppressible by FHV\B2^UAS.HM/Scer\GAL4^GMR.PF

(Chou et al., 2007)

hid^GMR.PG has eye phenotype, non-suppressible by NDV\B2^UAS.HM/Scer\GAL4^GMR.PF

(Chou et al., 2007)

hid^GMR.PG has eye phenotype, non-suppressible by Scer\GAL4^GMR.PF/VV\E3L^UAS.HM

(Chou et al., 2007)

hid^GMR.PG has eye phenotype, non-suppressible by TBSV\P19^UAS.HM/Scer\GAL4^GMR.PF

(Chou et al., 2007)

hid^GMR.PG has eye phenotype, non-suppressible by Scer\GAL4^GMR.PF/Ivir\NS1^UAS.HM

(Chou et al., 2007)

hid^GMR.PG has eye phenotype, non-suppressible by CtBP^GSA132/Scer\GAL4^GMR.PF

(Fang et al., 2006)

hid^GMR.PG has eye phenotype, non-suppressible by Scer\GAL4^GMR.PF/CtBP^GSA396

(Fang et al., 2006)

hid^GMR.PG has eye phenotype, non-suppressible by Scer\GAL4^Tub.PU/upd1^UAS.cZa

(Herz et al., 2006)

hid^GMR.PG has eye phenotype, non-suppressible by Dredd^B118

(Kondo et al., 2006)

hid^GMR.PG has eye phenotype, non-suppressible by Decay^ΔK2/Decay^ΔK2

(Kondo et al., 2006)

hid^GMR.PG has eye phenotype, non-suppressible by Dcp-1^Prev1/Dcp-1^Prev1

(Kondo et al., 2006)

hid^GMR.PG has eye phenotype, non-suppressible by Fadd^RNAi.UAS.cLa/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, non-suppressible by Scer\GAL4^GMR.PF/Damm^RNAi.UAS.cLa

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, non-suppressible by Dredd^RNAi.UAS.cLa/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, non-suppressible by Dcp-1^RNAi.UAS.cLa/Scer\GAL4^GMR.PF

(Leulier et al., 2006)

hid^GMR.PG has eye phenotype, non-suppressible by Dronc¹¹/Nc[+]

(Waldhuber et al., 2005)

hid^GMR.PG has eye phenotype, non-suppressible by Dronc⁵¹/Nc[+]

(Waldhuber et al., 2005)

hid^GMR.PG has eye phenotype, non-suppressible by Dronc³⁰/Nc[+]

(Waldhuber et al., 2005)

hid^GMR.PG has eye | somatic clone phenotype, non-suppressible by Dronc^I24/Nc[+]

(Xu et al., 2005)

hid^GMR.PG has eye phenotype, non-suppressible by Dark^unspecified/Ark[+]

(Gottfried et al., 2004)

hid^GMR.PG has eye phenotype, non-suppressible by Mad^unspecified

(Bach et al., 2003)

hid^GMR.PG has eye phenotype, non-suppressible by Stat92E^unspecified

(Bach et al., 2003)

hid^GMR.PG has eye phenotype, non-suppressible by spen^DN.UAS/Scer\GAL4^GMR.PF

(Lin et al., 2003)

hid^GMR.PG has eye phenotype, non-suppressible by TER94[+]/TER94^26-8

(Higashiyama et al., 2002)

hid^GMR.PG has phenotype, non-suppressible by Ubc2^k13206

(Ryoo et al., 2002)

hid^GMR.PG has phenotype, non-suppressible by lwr^unspecified

(Ryoo et al., 2002)

hid^GMR.PG has phenotype, non-suppressible by S^EM2-4

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-suppressible by SM2-1^SM2-1

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-suppressible by SM3-2^SM3-2

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-suppressible by SM3-3^SM3-3

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-suppressible by SM3-6^SM3-6

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-suppressible by SM3-8^SM3-8

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-suppressible by bul^SF3-1

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-suppressible by sty^SM3-5

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-suppressible by sty^SM3-9

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-suppressible by EM3-1^EM3-1

(Taguchi et al., 2000)

hid^GMR.PG has phenotype, non-suppressible by S^EF2-1

(Taguchi et al., 2000)

hid^GMR.PG has eye phenotype, non-suppressible by Dark^k11502

(Kanuka et al., 1999, Zhou et al., 1999)

hid^GMR.PG has phenotype, non-suppressible by Ras85D^V12.G37.UAS/Scer\GAL4^hs.2sev

(Bergmann et al., 1998)

Enhancer of

Statement

Reference

hid^GMR.PG is an enhancer of eye phenotype of Dcp-1^fl.GMR

(Song et al., 2000)

NOT Enhancer of

Statement

Reference

hid^GMR.PG is a non-enhancer of phenotype of Drice^fl.GMR

(Song et al., 2000)

Other

Statement

Reference

Scer\GAL4^αTub84B.PZ, ci^{Ce-2.UAS.Tag:HA}, cos^H29, hid^GMR.PG has eye phenotype

(Christiansen et al., 2013)

Df(1)N-8/+, cos^H29, hid^GMR.PG has eye phenotype

(Christiansen et al., 2013)

Delta^RevF10/Dl[+], Ser[+]/Ser^RX82, cos^H29, hid^GMR.PG has eye phenotype

(Christiansen et al., 2013)

Pka-C1^B3, Su(H)^del47, hid^GMR.PG has eye phenotype

(Christiansen et al., 2013)

Upf2^14J, hid^GMR.PG has eye | somatic clone phenotype

(Metzstein and Krasnow, 2006)

Additional Comments

Genetic Interactions

Statement

Reference

The small eye phenotype resulting from the cell death induced by expression of hid^GMR.PG is partially suppressed by combination with Dronc^I29 but not axed²⁰⁹⁴.

(Neukomm et al., 2017)

The strongly reduced eye size characteristic for adult flies expressing hid^GMR.PG is partially reverted by expression of either Duba^GD11813 or Duba^KK108478 under the control of Scer\GAL4^GMR.PU or by combination with the Duba¹⁰⁷ allele in homozygous state.

(Koerver et al., 2016)

Drice¹⁷/Drice¹⁷, Drice¹⁷/Drice^Δ1, Drice¹⁷/Drice^L1, Drice¹⁷/Drice^L2, Drice¹⁷/Drice^C1, Drice¹⁷/Drice^C2, Drice¹⁷/Drice^S1, Drice¹⁷/Drice^S2 (but not Drice¹⁷/+) significantly suppresses the eye ablation phenotype in hid^GMR.PG flies. Drice^L1/+ weakly suppresses the eye ablation phenotype in hid^GMR.PG flies.

(Wu et al., 2016)

Expression of Corp^EY03495 under the control of Scer\GAL4^GMR.PF suppresses the increased cell death and reduced eye phenotypes caused by expression of hid^GMR.PG.

p53^5A-1-4 suppresses the reduced eye phenotypes caused by expression of hid^GMR.PG.

(Chakraborty et al., 2015)

Expression of CG3251^GD10916 under the control of Scer\GAL4^GMR.PF suppresses the hid^GMR.PG-induced small eye phenotype.

Expression of CG3251^KK106465 under the control of Scer\GAL4^GMR.PF suppresses the hid^GMR.PG-induced small eye phenotype.

(Louis et al., 2015)

Expression of Ret^GMR.PR partially suppresses the reduction in eye size seen in flies expressing hid^GMR.PG. This suppression is partially reversed when Fak^{Scer\UAS.T:Ivir\HA1} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of Fak^{Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^GMR.PU does not have a significant effect on the reduced eye size seen upon expression of hid^GMR.PG.

(Macagno et al., 2014)

Eyes mosaic for cos^H29, cos^L51, cos^P50, ptc^C, ptc^L49, Pka-C1^K2 or Pka-C1^B3 (generated using the ey-FLP/FRT system) moderately suppress the W^GMR.PG eye phenotype. This suppression is cell non-autonomous.

Eyes mosaic for smo^D16 (generated using the ey-FLP/FRT system) enhance the W^GMR.PG eye phenotype.

Eye discs mosaic for cos^H29 (generated using the ey-FLP/FRT system) suppress the W^GMR.PG cell death phenotype by increasing the apoptosis resistance of neighbouring non-mutant cells - cos^H29 clones themselves are unprotected from W^GMR.PG-induced apoptosis. This cell non-autonomous suppression occurs only in the first, and not the second, apoptotic wave.

Eyes mosaic for Uba1^H42 (generated using the ey-FLP/FRT system) suppress the W^GMR.PG eye phenotype. This suppression is cell autonomous.

The suppression of the W^GMR.PG eye phenotype seen in eyes mosaic for cos^H29 (generated using the ey-FLP/FRT system) is reverted by expression of ci^{Ce-2.Scer\UAS.T:Ivir\HA1} (via the MARCM system) in the cos^H29 clones.

The suppression of the W^GMR.PG eye phenotype seen in eyes mosaic for cos^H29 (generated using the ey-FLP/FRT system) is abrogated by heterozygosity for Df(1)N-8, or both Dl^RevF10 and Ser^RX82.

The suppression of the W^GMR.PG eye phenotype seen in eyes mosaic for Pka-C1^B3 (generated using the ey-FLP/FRT system) is partially reverted if these clones are also mutant for Su(H)^del47.

(Christiansen et al., 2013)

A Cdk7^S164A.T170A mutant background significantly suppresses the partial eye ablation found upon expression of W^GMR.PG in the developing eye.

(Morishita et al., 2013)

NetA^Δ partially suppresses the cell death seen in flies expressing W^GMR.PG, resulting in increased eye size.

NetB^Δ enhances the cell death seen in flies expressing W^GMR.PG, resulting in a further reduced eye size.

Df(1)NetAB^Δ has little effect on the cell death seen in the eye of flies expressing W^GMR.PG. Flies continue to have small eyes compared to controls.

(Newquist et al., 2013)

Clbn^1Q/Clbn^1Q does not suppress the induction of apoptosis seen in hid^GMR.PG third instar eye discs.

(Wang et al., 2013)

Early third instar larvae expressing shi^{K44A.Scer\UAS} under the control of "BL-Gal4" (a combination of Scer\GAL4^elav.PLu, Scer\GAL80^tsh-GAL80 and Scer\GAL80^Cha.PK) at the restrictive temperature and also carrying W^GMR.PG show a normal avoidance response to a spot of intense light.

(Berni et al., 2012)

Expression of Bruce^BIR.Scer\UAS or Bruce^{Scer\UAS.T:Hsap\MYC} in the developing eye under the control of Scer\GAL4^GMR.PF weakly suppresses the small eye phenotype seen in W^GMR.PG mutants.

(Domingues and Ryoo, 2012)

Homozygous Ect4⁸⁹⁶ clones fail to suppress the cell death in the eye caused by W^GMR.PG.

(Osterloh et al., 2012)

Expression of Ack^Scer\UAS.cSb under the control of Scer\GAL4^GMR.PU greatly suppresses the reduced eye size caused by W^GMR.PG.

Expression of Ack^{K156A.Scer\UAS} under the control of Scer\GAL4^GMR.PU does not modify the reduced eye size caused by W^GMR.PG.

Homozygosity for Ack⁸⁶ enhances the reduced eye size caused by W^GMR.PG.

Expression of Ack^GD8506 under the control of Scer\GAL4^GMR.PU enhances the reduced eye size caused by W^GMR.PG.

Co-expression of Ack^Scer\UAS.cSb under the control of Scer\GAL4^GMR.PU suppresses the increased number of apoptotic cells seen posterior to the second mitotic wave and in the posterior region of the eye disc in the zone of compensatory proliferation in eye discs expressing W^GMR.PG.

Co-expression of drk^KK109233 does not modify eye size in animals expressing W^GMR.PG.

Expression of yki^Scer\UAS.cHa under the control of Scer\GAL4^GMR.PU suppresses the reduced eye size caused by W^GMR.PG and also results in a reduction in pigmentation.

yki^B5/+ does not suppress the reduced eye size caused by W^GMR.PG.

(Schoenherr et al., 2012)

Ras85D^R68Q suppresses W^GMR.PG induced cell death in a dosage-dependent manner.

(Gafuik and Steller, 2011)

Eye cell death observed in W^GMR.PG flies is suppressed by expression of Den1^VDRC.cUa under the control of Scer\GAL4^GMR.PF.

Eye cell death observed in W^GMR.PG flies is suppressed by expression of CSN5^NIG.14884R under the control of Scer\GAL4^GMR.PF.

Eye cell death observed in W^GMR.PG flies is suppressed by expression of CG1503^VDRC.cUa under the control of Scer\GAL4^GMR.PF.

Eye cell death observed in W^GMR.PG flies is suppressed in a Den1^EX9 mutant background.

(Broemer et al., 2010)

Expression of DJ-1α^Scer\UAS.cUa under the control of Scer\GAL4^GMR.PU is unable to rescue the eye phenotype of flies expressing hid^GMR.PG.

(Hao et al., 2010)

RNAi-mediated knockdown of rpr through expression of rpr^GD4698 in the developing eye under the control of Scer\GAL4^GMR.PF suppresses W^GMR.PG-induced eye ablation.

(Sandu et al., 2010)

The ectopic eye death seen in flies carrying W^GMR.PG is dominantly suppressed by morgue¹²⁶ and by morgue⁴⁵⁷.

(Schreader et al., 2010)

The eye-ablation phenotype in W^GMR.PG animals is suppressed in Vps25^N55 somatic clones generated in the eye-antennal imaginal disc in a non-autonomous manner.

The eye-ablation phenotype in W^GMR.PG animals is not suppressed in lsn^5F3-8 somatic clones generated in the eye-antennal imaginal disc.

The eye-ablation phenotype in W^GMR.PG animals is strongly suppressed in Vps36^L5212 somatic clones generated in the eye-antennal imaginal disc.

(Herz et al., 2009)

Scer\GAL4^GMR.PF-mediated expression of P{Sym-UAS-Hsrω} has a marginal rescue effect on the W^GMR.PG eye phenotype.

Scer\GAL4^GMR.PF-mediated expression of Hsrω^EP3037 does not discernibly enhance the W^GMR.PG eye phenotype, probably because W^GMR.PG eyes are already very damaged.

(Mallik and Lakhotia, 2009)

Expression of spen^{dsRNA.Scer\UAS} under the control of Scer\GAL4^GMR.PF fails to suppress the reduction in eye size seen in flies expressing W^GMR.PG.

Expression of nito^{dsRNA.Scer\UAS.cCa} under the control of Scer\GAL4^GMR.PF partially suppresses the reduction in eye size seen in flies expressing W^GMR.PG.

Co-expression of nito^{dsRNA.Scer\UAS.cCa} and spen^{dsRNA.Scer\UAS} under the control of Scer\GAL4^GMR.PF partially suppresses the reduction in eye size seen in flies expressing W^GMR.PG. The suppression is greater than is seen when nito^{dsRNA.Scer\UAS.cCa} is expressed alone.

(Chang et al., 2008)

The small eye phenotype caused by W^GMR.PG is moderately strongly suppressed by inducing homozygous clones of Uba1^D6 in the eye. A reduction in apoptotic cell death is seen in the double mutant eye discs compared to W^GMR.PG single mutants, with the suppression occurring in a region specific manner.

The small eye phenotype caused by W^GMR.PG is moderately strongly suppressed by inducing homozygous clones of Uba1^H33 or Uba1^H42 in the eye. The rescued eye tissue is homozygous for the Uba1 mutation in each case, indicating that the suppression is cell autonomous.

(Lee et al., 2008)

The small eye phenotype of W^GMR.PG eye clones is suppressed by a homozygous Cbl^K26, Cbl⁸, Cbl⁴, Cbl^L31, or Cbl⁷ background.

(Wang et al., 2008)

Iap2^E151 has little if any effect on the eye phenotype caused by W^GMR.PG.

(Huh et al., 2007)

Co-expression of PSR^Scer\UAS.cKa under the control of Scer\GAL4^GMR.PF partially suppresses the small rough eye seen in flies expressing W^GMR.PG.

The rough eye phenotype caused by W^GMR.PG is enhanced by one copy of PSR^FM1 and is further enhanced by two copies of PSR^FM1.

(Krieser et al., 2007)

The loss of eye tissue that is caused by W^GMR.PG is partially suppressed if the eye is also homozygous for Uba1^B2.

(Pfleger et al., 2007)

W^GMR.PG-induced ablation of the visual system results in rhythmic locomotory activity behaviour in flies expressing Scer\GAL4^P2.4.Pdf driven cry^{dsRNA.Scer\UAS.cPa} under constant light conditions. Wild-type flies do not show rhythmic behavior under the same conditions.

(Picot et al., 2007)

The W^GMR.PG eye ablation phenotype is strongly suppressed when eyes carry homozygous clones for the following mutations: Ark^A3b, Ark^A5, Ark^A24, Ark^B5, Ark^B15, Ark^C1, Ark^C4, Ark^D3, Ark^D4, Ark^E4, Ark^G8, Ark^G15, Ark^G29, Ark^H16, Ark^H28, Ark^H36, Ark^J15, Ark^L46, Ark^N28, Ark^N52, Ark^P13, Ark^P15, Ark^P46, Ark^P56, Ark^S7, Ark^S9.

The W^GMR.PG eye ablation phenotype is suppressed to a medium degree when eyes carry homozygous clones for the following mutations: Ark^B2, Ark^I1, Ark^J7, Ark^N5, Ark^N10.

The W^GMR.PG eye ablation phenotype is weakly suppressed when eyes carry homozygous clones for the following mutations: Ark^A6, Ark^M20.

The elevated apoptosis in W^GMR.PG eye discs is significantly reduced when eyes carry homozygous Ark^G8 clones.

(Srivastava et al., 2007)

The small eye phenotype generated by W^GMR.PG is not suppressed by expression of either the CtBP^GSA132 or the CtBP^GSA396 transgene (both under the control of Scer\GAL4^GMR.PF).

(Fang et al., 2006)

In Vps25^N55/Vps25^K2 mosaic eyes, in a W^GMR.PG background, the rescued tissue is genetically wild-type or heterozygous, suggesting that Vps25^N55 and Vps25^K2 mutant tissue does not contribute to the suppression of W^GMR.PG.

Vps25^K2 moderate-strongly suppresses the hid^GMR.PG eye phenotype.

Vps25^N55 moderate-strongly suppresses the hid^GMR.PG eye phenotype.

While overexpression of upd1^Scer\UAS.cZa in the eye gives rise to enlarged eyes, it is not sufficient to suppress hid^GMR.PG.

(Herz et al., 2006)

The reduction in adult eye size caused by expression of W^GMR.PG is suppressed if the eye is made homozygous for Nc^ΔA8 (using the eyFLP method).

The reduction in adult eye size caused by expression of W^GMR.PG is suppressed in a Ice^Δ2C8/Ice^Δ2C8 background.

The reduction in adult eye size caused by expression of W^GMR.PG is not suppressed in a decay^ΔK2/decay^ΔK2 or Dredd^B118 background.

The reduction in adult eye size caused by expression of W^GMR.PG is not suppressed if the eye is made homozygous for Dcp-1^Prev1 (using the eyFLP method).

The apoptosis posterior to the morphogenetic furrow that is induced by W^GMR.PG in third larval instar eye discs is completely suppressed in a Nc^ΔA8/Nc^ΔA8 background.

The apoptosis posterior to the morphogenetic furrow that is induced by W^GMR.PG in third larval instar eye discs is almost completely suppressed in a Ice^Δ2C8/Ice^Δ2C8 background.

(Kondo et al., 2006)

A W^GMR.PG background, used to eliminate all heterozygous and wild-type cells in the developing eye, Upf2^14J cells proliferate, differentiate, and form an eye, although the eyes are smaller and more disorganised (rougher) than those of controls.

(Metzstein and Krasnow, 2006)

The small eye phenotype exhibited by flies expressing W^GMR.PG is partially suppressed in a Ice^Δ1 homozygous background.

(Muro et al., 2006)

The small, rough eye phenotype of W^GMR.PG flies is partially suppressed by the expression of mir-278^{KN448.mirvana-1.Scer\UAS} under the control of Scer\GAL4^GMR.PF and strongly suppressed by mir-278^{KN447.Scer\UAS} under the control of Scer\GAL4^GMR.PF.

The eye phenotype of flies expressing W^GMR.PG is not enhanced by a mir-278^mirvana-1 or a mir-278^mirvana-1/Df(2R)Exel7137 background.

(Nairz et al., 2006)

Homozygous Ice¹⁷ clones induced in the eye suppress the eye ablation phenotype caused by W^GMR.PG.

The eye ablation phenotype caused by W^GMR.PG is suppressed if the flies are also carrying Ice¹⁷/Ice¹⁷ or Ice¹⁷/Df(3R)Ice.

The suppression is even stronger in Ice¹⁷ homozygous flies.

(Xu et al., 2006)

The creation of mats^e325 clones in the eye, significantly suppress the cell death and small eye phenotypes seen in mats^e325 animals.

(Lai et al., 2005)

The rough, small eye phenotype of W^GMR.PG is not suppressed by Nc¹¹/+, Nc⁵¹/+ or Nc³⁰/+.

(Waldhuber et al., 2005)

Reducing lz activity by transferring lz^ts1 W^GMR.PG flies to the non-permissive temperature of 33^oC partially suppresses the W^GMR.PG eye phenotype.

(Wildonger et al., 2005)

The severity of the W^GMR.PG eye phenotype is suppressed by "dronc[d5]" animals (Df(3L)Nc^Z in which CG6685 function, but not Nc function, is rescued by P{CG6685^+tDa}).

(Daish et al., 2004)

The reduced eye phenotype caused by expression of W^GMR.PG is significantly suppressed by pnut¹/+ or pnut^XP/+, but Ark^unspecified/+ has little effect.

(Gottfried et al., 2004)

W^GMR.PG; cry^b flies fail to entrain to light-dark cycles of even the highest amplitude.

W^GMR.PG; cry^b flies show anomalous rhythmicity in when kept in constant light, like cry^b flies.

W^GMR.PG; Pdf⁰¹ flies show similar weak short-period rhythmicity phenotypes when kept in constant darkness to Pdf⁰¹ single mutant flies.

(Klarsfeld et al., 2004)

klu^unspecified/+ strongly suppresses the eye phenotype caused by W^GMR.PG; the adult eye is dramatically increased in size and the pattern of the ommatidia is almost normal.

(Rusconi et al., 2004)

Eye size is largely restored by co-expression of ban^EP3622 (driven by Scer\GAL4^GMR.PF) with W^GMR.PG. The addition of Df(3L)ban^Δ1 to W^GMR.PG animals leads to a significant enhancement of the eye phenotype.

(Brennecke et al., 2003)

When scrib¹ clones are made in eyes expressing W^GMR.PG the viability of the mutant clones increases dramatically. This results in tissue overgrowth and lethality.

(Brumby and Richardson, 2003)

When hpo^BF33 clones are made in a W^GMR.PG background the resultant eyes are larger than that seen in W^GMR.PG animals alone.

(Jia et al., 2003)

W^GMR.PG-induced apoptosis is blocked in hpo^{dsRNA.Scer\UAS} mutant clones.

(Pantalacci et al., 2003)

Heterozygosity for nmo^unspecified partially rescues the small eye size of W^GMR.PG animals.

(Mirkovic et al., 2002)

The addition of W^GMR.PG to th⁵ heterozygotes leads to an enhancement of cell killing. The subsequent addition of Ark^CD4/Ark^CD4 suppresses that enhancement.

(Rodriguez et al., 2002)

The eye ablation phenotype of W^GMR.PG flies is partially suppressed by eff^D73/+.

(Ryoo et al., 2002)

When sav³ clones are induced in the eye disc in W^GMR.PG mutants, the induction of apoptosis is reduced in a cell autonomous manner.

(Tapon et al., 2002)

The ablated eye phenotype of rpr^GMR.PW flies is suppressed by th^21-4s or th^33-1s.

(Wilson et al., 2002)

The eye cell death phenotype caused by W^GMR.PG is suppressed by Df(2L)morgue¹⁹/+.

(Wing et al., 2002)

The W^GMR.PG severely ablated eye phenotype is significantly suppressed by Damm^{C156G.GMR.T:Zzzz\FLAG}.

(Harvey et al., 2001)

The addition of Ice^fl.GMR to W^GMR.PG produces no enhancement of either phenotype instead producing an additive effect. The addition of W^GMR.PG to Dcp-1^fl.GMR flies show a weak enhancement of the eye phenotype seen in these flies.

(Song et al., 2000)

The eye phenotype caused by expression of W^GMR.PG is not affected by Ark^k11502.

(Kanuka et al., 1999)

The W^GMR.PG eye phenotype is markedly suppressed if the flies are also homozygous for Ark^CD4.

(Rodriguez et al., 1999)

Ark^k11502 has little effect on the eye phenotype caused by W^GMR.PG.

(Zhou et al., 1999)

The reduced eye phenotype is markedly suppressed by Dsor1^Su1 and rl^Su23. The larval eye disc phenotype is also reduced in Dsor1^Su1 and rl^Su23 mutants.

(Sawamoto et al., 1998)

The small eye phenotype is dominantly enhanced by th mutations.

(Hay et al., 1995)

Xenogenetic Interactions

Statement

Reference

Co-expression of BacA\p35^GMR.PH completely suppresses the reduced eye size caused by W^GMR.PG.

(Schoenherr et al., 2012)

Expression of FHV\B2^Scer\UAS.HM in the developing eye, under the control of Scer\GAL4^GMR.PF fails to suppress the small, rough eye phenotype of hid^GMR.PG.

Expression of Zzzz\B2^Scer\UAS.HM in the developing eye, under the control of Scer\GAL4^GMR.PF fails to suppress the small, rough eye phenotype of hid^GMR.PG.

Expression of Zzzz\E3L^Scer\UAS.HM in the developing eye, under the control of Scer\GAL4^GMR.PF fails to suppress the small, rough eye phenotype of hid^GMR.PG.

Expression of Zzzz\p19^Scer\UAS.HM in the developing eye, under the control of Scer\GAL4^GMR.PF fails to suppress the small, rough eye phenotype of hid^GMR.PG.

Expression of Ivir\NS1^Scer\UAS.HM in the developing eye, under the control of Scer\GAL4^GMR.PF fails to suppress the small, rough eye phenotype of hid^GMR.PG.

Expression of BacA\p35^GMR.PH in the developing eye suppresses the small, rough eye phenotype of hid^GMR.PG.

(Chou et al., 2007)

Complementation and Rescue Data

Rescued by

hid^GMR.PG is rescued by hid^GD1673/Scer\GAL4^GMR.PF

(Sandu et al., 2010)

Comments

RNAi-mediated knockdown of W through expression of W^GD1673 in the developing eye under the control of Scer\GAL4^GMR.PF suppresses W^GMR.PG-induced eye ablation.

(Sandu et al., 2010)

Images (0)

Mutant

Wild-type

Stocks (16)

Bloomington

5771

P{GMR-hid}G1/CyO, P{sevRas1.V12}FK1

605355

w^*; P{GMR-hid.w^-}3/TM3, Sb¹

5248

P{GMR-hid}SS1, y¹ w^* P{neoFRT}19A; P{GAL4-ey.H}SS5, P{UAS-FLP.D}JD2