Allele Dmel\jv^c03230

General Information
Symbol	Dmel\jv^c03230	Species	D. melanogaster
Name		FlyBase ID	FBal0265580
Feature type	allele	Associated gene	Dmel\jv

Map ( GBrowse )	Untitled Document
Allele class	hypomorphic allele - molecular evidence
Mutagen
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class	hypomorphic allele - molecular evidence (Shapira et al., 2011)
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 3L:6,557,654..6,557,654 (Shapira et al., 2011)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Transcript levels are reduced 1.5-fold compared to wild type. (Shapira et al., 2011)
Caused by insertion	PBac{PB}CG18769^c03230 (Shapira et al., 2011)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	macrochaeta (Shapira et al., 2011) macrochaeta (with jv¹) (Shapira et al., 2011)
Detailed Description
	Statement Reference jv[c03230] and jv[c03230]/jv[1] show defects in bristle development similar to jv[1]. (Shapira et al., 2011)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Partially rescued by	jv¹/jv^c03230 is partially rescued by jv^{Scer\UAS.P\T.T:Avic\GFP}/Scer\GAL4^Act5C.PU (Shapira et al., 2011)
Comments	Scer\GAL4[Act5C.PU]-mediated expression of jv[Scer\UAS.P\T.T:Avic\GFP] partially rescues the swollen bristle tip and fused posterior scutellar bristle phenotypes of jv[1]/jv[c03230] flies. Bristle ridges are more pronounced, though ridges still do not run parallel to each other. (Shapira et al., 2011)
Stocks ( 1 )
Bloomington	11220 w¹¹¹⁸; PBac{PB}CG18769^c03230
Notes on Origin
Discoverer

Comments
	Excision of the PBac element reverts the jv[c03230] bristle phenotype, and the excision line now complements jv[1]. (Shapira et al., 2011)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	jv² (Shapira et al., 2011) jv^c03230
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Shapira et al., 2011, Mol. Cell. Biol. 31(22): 4582--4592 The Drosophila javelin Gene Encodes a Novel Actin-Associated Protein Required for Actin Assembly in the Bristle. [FBrf0216490]

Allele Dmel\jvc03230

Allele Dmel\jv^c03230