|Feature type||allele||Associated gene||Dmel\Caf1|
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|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
Amino acid replacement: Q79@.
|Phenotype Manifest In|
Homozygous larvae appear grossly normal but mature slowly and die as first or second instars. Homozygous clones induced using hs-FLP do not survive in adults. Homozygous clones in the eye which have been generated using the ey-FLP; FRT cell lethal system are very small, comprising only a small portion of the eye. The remaining eye is small, highly disorganised and almost completely devoid of bristles. Approximately 20% of flies containing ey-FLP induced clones have extra or missing appendages on the head, including the ocelli, antennae and maxillary palps. Homozygous clones in the third larval instar eye disc which have been generated using the ey-FLP; FRT cell lethal system are small, show extensive apoptosis and have an irregular arrangement of photoreceptor clusters. Homozygous clones have not been recovered in the adult thorax. Caf1[short]/Caf1[med] flies expressing Caf1[Scer\UAS.cAa] under the control of Scer\GAL4[Ubi] and raised at 18[o]C during the third larval instar stage have disorganised kidney-shaped eyes with abnormalities in the arrangement of rhabdomeres (including loss of small central rhabdomeres) and show homeotic transformation of the arista to leg-like structures that occasionally end in claws. These defects are not seen if the animals are raised at 25[o]C during the third larval instar stage.
|Phenotype Manifest In|
|Complementation & Rescue Data|
|Partially rescued by|
|Stocks ( 0 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 1 )|
|Secondary FlyBase IDs|
|References ( 1 )|