FB2025_01 , released February 20, 2025
Allele: Dmel\Skp2UASp.Tag:HA
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General Information
Symbol
Dmel\Skp2UASp.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0265628
Feature type
allele
Associated gene
Dmel\Skp2
Associated Insertion(s)
Carried in Construct
P{UASp-HA-Skp2}
Key Links
Transgenic product class
cDNA
(Ghorbani et al., 2011)
wild_type
(Ghorbani et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Ghorbani et al., 2011)
wild_type
(Ghorbani et al., 2011)
Mutagen
in vitro construct
(Ghorbani et al., 2011)
Progenitor genotype
Carried in construct
P{UASp-HA-Skp2}
Cytology
Description

UASp regulatory sequences drive expression of the Skp2 coding sequence (from the RE15215 cDNA) which is tagged at the N-terminal end with two copies of Tag:HA.

(Ghorbani et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Skp2
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Skp2Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4da.G32 partially rescues the lethality of Cks85Aex15 homozygotes: the animals progress to the pharate adult stage and die during or shortly after escaping from the pupal case.

      Expression of Skp2Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4da.G32 rescues the polyploidy seen anterior to the morphogenetic furrow in the eye discs of homozygous Cks85Aex15 wandering third instar larvae at 29[o]C.

      (Ghorbani et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Skp2UASp.Tag:HA/Scer\GAL4da.G32 rescues Skp2ex9

      (Ghorbani et al., 2011)
      Comments

      Expression of Skp2Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4da.G32 fully rescues the lethality of Skp2ex9.

      Expression of Skp2Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4da.G32 rescues the polyploidy seen in nuclei anterior to the morphogenetic furrow in the eye discs of Skp2ex9 homozygous larvae.

      (Ghorbani et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Skp2Scer\UAS.P\T.T:Ivir\HA1
      Skp2UASp.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (2)