Rae1EX28 mutants survive until the second instar larval stage. The mutant larvae start wandering with a body size close to second instar. They continue to wander for several days without a further increase in their body size and eventually die before pupation.
Rae1EX28 and Rae1EX28/Df(2R)XE-2900 mutant neuromuscular junctions exhibit synaptic terminal overgrowth and decreased bouton size in synapses on muscle 6/7. The average muscle size in these mutants appears similar to controls.