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General Information
Symbol
Dmel\DarkdsRNA.UAS.cLa
Species
D. melanogaster
Name
FlyBase ID
FBal0265673
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an inverted repeat of a fragment of Dark.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

No apoptosis is observed in the dorsal compartment of the wing imaginal disc when ArkdsRNA.Scer\UAS.cLa is expressed under the control of Scer\GAL4ap-md544.

Animals expressing ArkdsRNA.Scer\UAS.cLa under the control of Scer\GAL4αTub84B.PL have high levels of pupal lethality, and rare escapers display wing defects and supernumeral bristles.

Animals expressing ArkdsRNA.Scer\UAS.cLa under the control of Scer\GAL4GMR.PF have an aberrant number of pupal retinal lattice cells (68 hours after puparium formation).

Expression of ArkdsRNA.Scer\UAS.cLa in the salivary glands under the control of Scer\GAL434B delays salivary gland histolysis during pupal development.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of DarkdsRNA.Scer\UAS.cLa under the control of Scer\GAL4da.PU suppresses the age-dependent loss of rhabdomeres seen in YME1Ldel homozygotes.

Expression of DarkdsRNA.Scer\UAS.cLa under the control of Scer\GAL4da.PU partially suppresses the age-dependent locomotor defect seen in YME1Ldel homozygotes.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Carried in a plasmid and transfected into S2 cells. Transcription from the plasmid should produce Ark dsRNA, resulting in dsRNA interference (RNAi) of the Ark gene.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
ArkdsRNA.Scer\UAS.cLa
ArkdsRNA.Scer\UAS
DarkdsRNA.Scer\UAS.cLa
DarkdsRNA.UAS.cLa
Name Synonyms
Secondary FlyBase IDs
  • FBal0244094
  • FBal0194835
References (5)