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General Information
Symbol
Dmel\mir-34UAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Liu
FlyBase ID
FBal0265722
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of the mir-34 primary stem loop precursor.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing mir-34Scer\UAS.cLa under the control of Scer\GAL4ninaE.PT have a normal number of photoreceptors per ommatidium.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Expression of mir-34Scer\UAS.cLa partially suppresses the degeneration seen when Hsap\ATXN3tr.Q78.Scer\UAS.T:Ivir\HA1 is expressed under the control of Scer\GAL4ninaE.PT. Inclusion formation is slowed, the protein retains greater solubility and neural degeneration is suppressed. The reduced number of photoreceptors per ommatidium seen in 21 day old flies is also partially rescued.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
mir-34Scer\UAS.cLa
mir-34UAS.cLa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Liu
Secondary FlyBase IDs
    References (2)