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General Information
Symbol
Dmel\zipHMS01618
Species
D. melanogaster
Name
FlyBase ID
FBal0266525
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-zip-RNAi
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adult flies expressing zipHMS01618 under the control of Scer\GAL4Dot.PK display nephrocyte functional defects (measured by uptake assays) and reduced adult lifespan relative to controls.

Expression of zipHMS01618 under the control of Scer\GAL4GMR.PU results in fused rhabdomeres.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference

zipHMS01618/Scer\GAL4GMR.PU is an enhancer of retina phenotype of eys1, prom[+]/prom1

Other
Statement
Reference

eys[+]/eys1, zipHMS01618 has retina phenotype

Additional Comments
Genetic Interactions
Statement
Reference

Expression of zipHMS01618 under the control of Scer\GAL4GMR.PU enhances the rhabdomere fusion seen in eys1 prom1 double heterozygotes.

Expression of zipHMS01618 under the control of Scer\GAL4GMR.PU in a eys1 mutant background results in fused rhabdomeres as early as 48 hours after pupal formation.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
zipHMS01618
Name Synonyms
Secondary FlyBase IDs
    References (7)