Allele Dmel\18w^g.Scer\UAS

General Information
Symbol	Dmel\18w^g.Scer\UAS	Species	D. melanogaster
Name		FlyBase ID	FBal0267025
Feature type	allele	Associated gene	Dmel\18w

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of a genomic fragment containing the 18w coding sequence. (Yagi et al., 2010)
Carried in construct	P{UAS-18w.g} (Yagi et al., 2010)
Cytology
Phenotypic Data
Phenotypic Class
	lethal, with Scer\GAL4^32B (Yagi et al., 2010) lethal, with Scer\GAL4^da.G32 (Yagi et al., 2010) lethal, with Scer\GAL4^e22c (Yagi et al., 2010) lethal, with Scer\GAL4^ptc-559.1 (Yagi et al., 2010)
Phenotype Manifest In
	adult abdomen, with Scer\GAL4^71B (Yagi et al., 2010) eye, with Scer\GAL4^71B (Yagi et al., 2010) eye, with Scer\GAL4^GMR.PF (Yagi et al., 2010) eye, with Scer\GAL4^lz-gal4 (Yagi et al., 2010) leg, with Scer\GAL4^dpp.PS (Yagi et al., 2010) macrochaeta \| ectopic, with Scer\GAL4^71B (Yagi et al., 2010) ventral thoracic disc, with Scer\GAL4^dpp.PS (Yagi et al., 2010) wing, with Scer\GAL4^dpp.PS (Yagi et al., 2010) wing disc, with Scer\GAL4^dpp.PS (Yagi et al., 2010)
Detailed Description
	Statement Reference Expression of 18w[g.Scer\UAS] under the control of either Scer\GAL4[GMR.PF] or Scer\GAL4[lz-gal4] generates a rough eye phenotype. Expression of 18w[g.Scer\UAS] under the control of Scer\GAL4[71B] results in a closure defect in the adult abdomen, an extra bristle phenotype and a rough eye phenotype. Expression of 18w[g.Scer\UAS] under the control of Scer\GAL4[dpp.PS] results in small wings that bifurcate along the anterior-posterior boundary along with leg defects. This defect can be traced to the imaginal disc stage, where abnormal folding at the anterior-posterior boundary is found. (Yagi et al., 2010)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	18w^g.Scer\UAS
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Yagi et al., 2010, Dev. Growth Differ. 52(9): 771--783 Functional analysis of Toll-related genes in Drosophila. [FBrf0212564]

Allele Dmel\18wg.Scer\UAS

Allele Dmel\18w^g.Scer\UAS