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General Information
Symbol
Dmel\Pgam5NIG.14816R
Species
D. melanogaster
Name
FlyBase ID
FBal0267418
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASt regulatory sequences drive expression of an inverted repeat corresponding to Pgam5.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Flies expressing Pgam5NIG.14816R under the control of Scer\GAL4da.G32 are sensitive to heat shock stress and die sooner than control flies. Heat shock sensitivity is also seen when Pgam5NIG.14816R is expressed under the control of Scer\GAL4hs.PU for 4X 30 minutes at 37[o]C prior to heat shock treatment. Expression of Pgam5NIG.14816R in the fat body (under the control of Scer\GAL4yolk), hemocytes (Scer\GAL4Pxn.PS), eye (Scer\GAL4hs.2sev), bristle (Scer\GAL4sca-P309) or mediodorsal parts of the thoracic and abdominal segments (Scer\GAL4pnr-MD237) has no effect on heat shock sensitivity compared to controls. An increase in sensitivity is seen when Pgam5NIG.14816R is expressed in the mushroom body under the control of either Scer\GAL4c739, Scer\GAL4ey-OK107 or Scer\GAL4Tab2-201Y and expression under the control of Scer\GAL4elav-C155 also induced the vulnerability of flies to heat shock. No change in sensitivity is seen when Pgam5NIG.14816R is expressed in dopaminergic neurons under the control of Scer\GAL4ple.PF.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Pgam5NIG.14816R-6
Pgam5NIG.14816R
Name Synonyms
Secondary FlyBase IDs
    References (2)