FB2025_01 , released February 20, 2025
Allele: Dmel\HersUAS.Tag:FLAG
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General Information
Symbol
Dmel\HersUAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0267762
Feature type
allele
Associated gene
Dmel\Hers
Associated Insertion(s)
Carried in Construct
P{UAS-Hers.FLAG}
Key Links
Transgenic product class
cDNA
(Ito et al., 2012)
wild_type
(Ito et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Ito et al., 2012)
wild_type
(Ito et al., 2012)
Mutagen
in vitro construct
(Ito et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Hers.FLAG}
Cytology
Description

UAS drives expression of a Tag:FLAG-tagged Hers cDNA.

(Ito et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hers
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4GMR.PU-mediated expression of HersScer\UAS.T:Zzzz\FLAG results in a rough eye.

      Scer\GAL4GMR.PU-mediated expression of HersScer\UAS.T:Zzzz\FLAG suppresses the In(1)wm4h mottled eye phenotype, resulting in red eyes.

      (Ito et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      HersUAS.Tag:FLAG, Scer\GAL4GMR.PU has eye phenotype, enhanceable by Su(var)3-91

      (Ito et al., 2012)

      HersUAS.Tag:FLAG, Scer\GAL4GMR.PU has eye phenotype, enhanceable by Su(var)2054

      (Ito et al., 2012)
      NOT Enhanced by
      Statement
      Reference

      HersUAS.Tag:FLAG, Scer\GAL4GMR.PU has eye phenotype, non-enhanceable by Su(var)2-101

      (Ito et al., 2012)
      NOT suppressed by
      Statement
      Reference

      HersUAS.Tag:FLAG, Scer\GAL4GMR.PU has eye phenotype, non-suppressible by Su(var)2-101

      (Ito et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The Scer\GAL4GMR.PU, HersScer\UAS.T:Zzzz\FLAG rough eye phenotype is significantly enhanced by Su(var)3-91 or Su(var)2054, while Su(var)2-101 has no effect.

      (Ito et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      HersUAS.Tag:FLAG is rescued by HersRNAi.UAS/Scer\GAL4GMR.PU

      (Ito et al., 2012)
      Comments

      The Scer\GAL4GMR.PU, HersScer\UAS.T:Zzzz\FLAG rough eye phenotype is rescued by coexpression of HersdsRNA.Scer\UAS.

      (Ito et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      HersScer\UAS.T:Zzzz\FLAG
      HersUAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)