FB2025_01 , released February 20, 2025
Allele: Scer\GAL4ppk23.2.6
Open Close
General Information
Symbol
Scer\GAL4ppk23.2.6
Species
S. cerevisiae
Name
FlyBase ID
FBal0267802
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{ppk23-GAL4.2.6}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Lu et al., 2012)
Progenitor genotype
Carried in construct
P{ppk23-GAL4.2.6}
Cytology
Description

A 2.6kb fragment (nucleotides X:17402154..17404754 , release 5 genome) which includes the ppk23 first intron is fused upstream of sequence encoding a GAL4 driver.

(Lu et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
ppk23
ppk23_ppk23-promoter-GAL4
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      prothoracic leg taste bristle chemosensory neuron

      Comment: Stronger expression in males.

      (Lu et al., 2012)
      mesothoracic leg taste bristle chemosensory neuron
      (Lu et al., 2012)
      metathoracic leg taste bristle chemosensory neuron
      (Lu et al., 2012)
      chemosensory neuron | subset of wing margin bristle
      (Lu et al., 2012)
      adult ventral nerve cord | restricted
      (Lu et al., 2012)
      Additional Information
      Statement
      Reference

      ScerGAL4ppk23.2.6 drives expression in pairs of chemosensory neurons in the forelegs, middle legs and hind legs of both males and females. The number of neurons labeled in male forelegs is significantly higher than in females. Most of the male foreleg neurons labeled with ScerGAL4ppk23.2.6 also express EcollexAfru.P1.T:HsimVP16. Expression of ScerGAL4ppk23.2.6 also labels the axonal projections of the chemosensory neurons in the thoracico-abdominal ganglion. These projections are sexually dimorphic: midline crossing is observed only in males.

      (Lu et al., 2012)
       
      Marker for
      Reflects expression of
      ppk23
      (Lu et al., 2012)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4ppk23.2.6
      Name Synonyms
      Secondary FlyBase IDs
        References (3)