Allele Dmel\Eip71CD^Scer\UAS.cCa

General Information
Symbol	Dmel\Eip71CD^Scer\UAS.cCa	Species	D. melanogaster
Name	Saccharomyces cerevisiae UAS construct a of Chung	FlyBase ID	FBal0267949
Feature type	allele	Associated gene	Dmel\Eip71CD

Allele class
Mutagen
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS drives expression of Eip71CD coding sequences. (Chung et al., 2010)
Carried in construct	P{UAS-Eip71CD.C} (Chung et al., 2010)
Cytology
Phenotypic Data
Phenotypic Class
	increased cell number, with Scer\GAL4^GMR.PU (Chung et al., 2010) long lived \| RU486 conditional, with Scer\GAL4^{elav.Switch.PO} (Chung et al., 2010) oxidative stress response defective, with Scer\GAL4^arm.PS (Chung et al., 2010) size defective, with Scer\GAL4^GMR.PU (Chung et al., 2010)
Phenotype Manifest In
	eye, with Scer\GAL4^GMR.PU (Chung et al., 2010)
Detailed Description
	Statement Reference Oxidative stress-induced lethality declines when Eip71CD[Scer\UAS.cCa] is expressed using Scer\GAL4[arm.PS]. Moreover, median survival rate of these flies following exposure to paraquat is higher compared to controls. When Eip71CD[Scer\UAS.cCa] is expressed under the control of Scer\GAL4[elav.Switch.PO] and activated using RU486, both female and male lifespan is extended. Expression of Eip71CD[Scer\UAS.cCa] using Scer\GAL4[GMR.PU] results in increased irregularity and a rough eye phenotype. Eye size and cell number is increased. (Chung et al., 2010)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
NOT Enhanced by
Statement Reference Eip71CD^Scer\UAS.cCa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by bsk^DN.Scer\UAS, Scer\GAL4^GMR.PU (Chung et al., 2010)
NOT suppressed by
Statement Reference Eip71CD^Scer\UAS.cCa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by bsk^DN.Scer\UAS, Scer\GAL4^GMR.PU (Chung et al., 2010)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Eip71CD^Scer\UAS.cCa
Name Synonym	Saccharomyces cerevisiae UAS construct a of Chung
Secondary FlyBase IDs

References ( 1 )
Research paper	Chung et al., 2010, FEBS Lett. 584(16): 3609--3614 The Drosophila homolog of methionine sulfoxide reductase A extends lifespan and increases nuclear localization of FOXO. [FBrf0211506]

Allele Dmel\Eip71CDScer\UAS.cCa

Allele Dmel\Eip71CD^Scer\UAS.cCa