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General Information
Symbol
Dmel\EgfrUAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0268507
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-EGFR, UAS-EGFRwt
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of Egfr.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adulthood-only expression of EgfrUAS.cUa under the combined control of Scer\GAL4esg.PU and Gal80[ts], induced by temperature shift to 29[o]C for 1-6 days during adulthood, leads to a mild increase in the number of mitotic cells (phospho-H3 staining) per adult midgut, as compared to controls.

Overexpression of the wild-type EgfrScer\UAS.cUa construct in the posterior wing compartment, under the control of Scer\GAL4en-e16E results in excess wing vein tissue is formed between L4 and L5.

Overexpression of EgfrScer\UAS.cUa under the control of Scer\GAL4Ser.PGF results in extra wing veins around the dorso-ventral boundary.

Overexpression of EgfrScer\UAS.cUa via Scer\GAL4sca-537.4 results in extra bristles on the notum

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

EgfrUAS.cUa, Scer\GAL4sca-537.4 has visible phenotype, enhanceable by pum01688/pum[+]

EgfrUAS.cUa, Scer\GAL4sca-537.4 has visible phenotype, enhanceable by pumMsc/pum[+]

Enhancer of
NOT Enhancer of
Statement
Reference
Suppressor of
NOT Suppressor of
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-overexpression of pumScer\UAS.cKa with EgfrScer\UAS.cUa under the control of Scer\GAL4Ser.PGF suppressed the development of ectopic wing veins resulting from the overexpression of EgfrScer\UAS.cUa alone generating wings that are indistinguishable from those overexpressing pumScer\UAS.cKa alone.

Heterozygous pum01688 greatly enhances the ectopic macrochaeta phenotype induced by EgfrScer\UAS.cUa overexpression in the notum under the control of Scer\GAL4sca-537.4.

Heterozygous pumMsc greatly enhances the ectopic macrochaeta phenotype induced by EgfrScer\UAS.cUa overexpression in the notum under the control of Scer\GAL4sca-537.4.

Co-overexpression of pumScer\UAS.cKa and EgfrScer\UAS.cUa in the notum under the control of Scer\GAL4sca-537.4 suppresses the EgfrScer\UAS.cUa-induced ectopic macrochaeta phenotype.

Concomitant expression of pumHD.Scer\UAS.T:SV5\V5 with EgfrScer\UAS.cUa is able to suppress the EgfrScer\UAS.cUa-induced ectopic bristle formation in the notum.

Xenogenetic Interactions
Statement
Reference

The age-progressive memory induced by expression of Hsap\APPAβ1-42.Scer\UAS.cIa under the control of Scer\GAL4elav.PU is enhanced by co-expression of EgfrScer\UAS.cUa : the memory defect are detectable even in young 5-day-old flies that perform normally in the aversive olfactory memory assay when expressing Hsap\APPAβ1-42.Scer\UAS.cIa alone.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
EgfrScer\UAS.cUa
EgfrUAS.cUa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Unknown
Secondary FlyBase IDs
    References (6)