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General Information
Symbol
Dmel\SmoxdsRNA.UAS.cPa
Species
D. melanogaster
Name
FlyBase ID
FBal0268514
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of an RNAi construct targeting nt 1469-1928 of the Smox transcript.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Ubiquitous expression of SmoxdsRNA.Scer\UAS.cPa under the control of Scer\GAL4da.G32 results in widening of the larval wing disc. Widening is also seen with the pan-wing disc drivers Scer\GAL4sd-SG29.1 or Scer\GAL432B, No widening is seen when SmoxdsRNA.Scer\UAS.cPa is expressed under the control of either of the partial wing disc drivers Scer\GAL4nub-AC-62 or Scer\GAL4tsh-md621, but widening is detected when both drivers are used simultaneously. No widening is seen with the partial wing disc drivers Scer\GAL4A9 or Scer\GAL471B and minimal widening is seen with Scer\GAL4C-765. Wings discs expressing SmoxdsRNA.Scer\UAS.cPa with either Scer\GAL4C-765 or Scer\GAL4nub-AC-62 and the prothoracic gland driver Scer\GAL4phm.PO also appear normal. Expression of SmoxdsRNA.Scer\UAS.cPa under the control of Scer\GAL4esg-05730B also produces the wing disc widening phenotype.
Expression of SmoxdsRNA.Scer\UAS.cPa under the control of Scer\GAL4vg.MQ.Exel results in moderately blistered wings.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Co-expression of babodsRNA.Scer\UAS suppresses the wing discs widening phenotype seen in third instar larvae expressing SmoxdsRNA.Scer\UAS.cPa under the control of Scer\GAL4esg-05730B.
Co-expression of SmoxdsRNA.Scer\UAS.cPa with baboQ302D.Scer\UAS under the control of Scer\GAL4vg.MQ.Exel makes the baboQ302D.Scer\UAS-induced phenotype more severe. The resulting wings are more wrinkled and shrunken than wings where either construct is expressed alone.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
SmoxdsRNA.Scer\UAS.cPa
SmoxdsRNA.UAS.cPa
Name Synonyms
Secondary FlyBase IDs
    References (3)