Open Close
General Information
Symbol
Dmel\Src42ANIG.7873R
Species
D. melanogaster
Name
FlyBase ID
FBal0268977
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-src42A-IR
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a 500bp inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Reducing expression of Src42A (through expression of Src42ANIG.7873R under the control of Scer\GAL4btl.PS and one copy of Src42A26-1) delays the extension of the dorsal branch so that it lags behind the normally concurrent process of dorsal closure. The dorsal branch also contains fewer stalk cells. The dorsal trunk is a zigzag shape.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

Loss of Src42A, through expression of Src42ANIG.7873R, dramatically suppresses tumour cell invasion into the ventral nerve cord found in Ras85DV12.Scer\UAS/l(2)gl4 mutants and enables the animals to survive to the pupal stage, whereas the tumour size remains largely unaffected.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Src42ANIG.7873R
Name Synonyms
Secondary FlyBase IDs
    References (5)