Allele Dmel\Rat\Neu^YC.Scer\UAS

General Information
Symbol	Dmel\Rat\Neu^YC.Scer\UAS	Species	D. melanogaster
Name		FlyBase ID	FBal0269182
Feature type	allele	Associated gene	Dmel\Rat\Neu

Allele class
Mutagen	in vitro construct - amino acid replacement
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - amino acid replacement (Settle et al., 2003)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	Rat\Neu^{NYPD.Scer\UAS} (Settle et al., 2003)
Nature of the lesion	Statement Reference Amino acid residue 1201 has been restored to a Tyr residue. (Settle et al., 2003)
Carried in construct	P{UAS-Neu.YC} (Settle et al., 2003)
Cytology
Phenotypic Data
Phenotypic Class
	lethal, with Scer\GAL4^GMR.PU (Settle et al., 2003) visible, with Scer\GAL4^bbg-C96 (Settle et al., 2003) visible, with Scer\GAL4^GMR.PU (Settle et al., 2003)
Phenotype Manifest In
	eye, with Scer\GAL4^GMR.PU (Settle et al., 2003) midline glial cell \| embryonic stage 16 \| supernumerary, with Scer\GAL4^sim.P3.7 (Settle et al., 2003) ommatidium, with Scer\GAL4^GMR.PU (Settle et al., 2003) wing margin, with Scer\GAL4^bbg-C96 (Settle et al., 2003)
Detailed Description
	Statement Reference Expression of Rat\Neu[YC.Scer\UAS] under the control of Scer\GAL4[sim.P3.7] results in a slightly increased number of midline glia cells compared to wild type at stage 16 of embryogenesis. The 1.3% of animals expressing Rat\Neu[YC.Scer\UAS] under the control of Scer\GAL4[GMR.PU] which survive to eclosion have a severely reduced eye with no ommatidial structure. Flies expressing Rat\Neu[YC.Scer\UAS] under the control of Scer\GAL4[bbg-C96] have notches on the the wing margin. (Settle et al., 2003)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	neu^YC (Settle et al., 2003) Rat\Neu^YC.Scer\UAS
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Settle et al., 2003, Oncogene 22(13): 1916--1926 Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model. [FBrf0159278]

Allele Dmel\Rat\NeuYC.Scer\UAS

Allele Dmel\Rat\Neu^YC.Scer\UAS