Most embryos from Cad99C^57A/Cad99C^120B females are not recoverable. Most (>90%) of these maternal and zygotic (M/Z)Cad99C-expressed embryos develop normally but have longer, thinner salivary glands than in wild-type; only a small subset of the recovered embryos show severe morphological defects. Embryos missing only maternal or only zygotic function do not have overt defects. No phenotypic differences are detected at the ultrastructural level in comparisons of stage 15/16 Cad99C[M/Z] mutant and wild-type salivary glands. The overall polarity of Cad99C[MZ] mutant salivary glands appear unaffected and the mutant salivary glands migrate normally, contacting the same tissues at all stages as wild-type salivary glands. Total cell numbers are not significantly different and the apical domain size and elongation ratio of individual cells is also unchanged. Indeed, the only difference is that fewer cells surround the lumen in cross-sections of the Cad99C[M/Z] mutant salivary glands compared with wild-type. Thus, the longer, thinner salivary gland lumen in Cad99C[M/Z] mutants reflect differences in cell rearrangement during tube elongation.

Eggs laid by homozygous females spontaneously collapse after deposition and do not develop into larvae. These eggs are nearly all permeable to the dye Neutral Red after dechorionation, suggesting a vitelline membrane defect.

More than 80% of eggs laid by Cad99C^57A/Cad99C^120B and Cad99C^51C/Cad99C^120B females are permeable to the dye Neutral Red after dechorionation, suggesting a vitelline membrane defect.